Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin
Summary: Context-specific activities of transcription regulators (TRs) in the nucleus modulate spatiotemporal gene expression precisely. Using the largest ChIP-seq data and chromatin loops in the human K562 cell line, we initially interrogated TR cooperation in 3D chromatin via a graphical model and...
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Auteurs principaux: | , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Elsevier
2021
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Accès en ligne: | https://doaj.org/article/35a57d76d27143a89fd9b8af06327582 |
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