Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin

Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin

Summary: Context-specific activities of transcription regulators (TRs) in the nucleus modulate spatiotemporal gene expression precisely. Using the largest ChIP-seq data and chromatin loops in the human K562 cell line, we initially interrogated TR cooperation in 3D chromatin via a graphical model and...

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Bibliographic Details
Main Authors: Xianfu Yi, Zhanye Zheng, Hang Xu, Yao Zhou, Dandan Huang, Jianhua Wang, Xiangling Feng, Ke Zhao, Xutong Fan, Shijie Zhang, Xiaobao Dong, Zhao Wang, Yujun Shen, Hui Cheng, Lei Shi, Mulin Jun Li
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Genetics
Molecular genetics
Bioinformatics
Science
Q
Online Access:https://doaj.org/article/35a57d76d27143a89fd9b8af06327582
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https://doaj.org/article/35a57d76d27143a89fd9b8af06327582

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