Proteolysis regulates cardiomyocyte maturation and tissue integration
Proper heart development and synchronous cardiomyocyte contraction rely on tissue integrity. Here the authors show that the ubiquitin-proteasome system and the E3 ubiquitin ligase ASB2 in particular are crucial for cardiomyocyte maturation and tissue integrity through the degradation of the TCF3 tra...
Guardado en:
Autores principales: | Ryuichi Fukuda, Felix Gunawan, Arica Beisaw, Vanesa Jimenez-Amilburu, Hans-Martin Maischein, Sawa Kostin, Koichi Kawakami, Didier Y. R. Stainier |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/35ac95838d1a400d9bec92929d476124 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling
por: S. Javad Rasouli, et al.
Publicado: (2017) -
Transient cardiomyocyte fusion regulates cardiac development in zebrafish
por: Suphansa Sawamiphak, et al.
Publicado: (2017) -
Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level.
por: Suraj Kannan, et al.
Publicado: (2021) -
Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair
por: Deepika Dogra, et al.
Publicado: (2017) -
Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor
por: Yuxuan Guo, et al.
Publicado: (2018)