One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?

Liver is the main target organ for colorectal cancer (CRC) metastases. It is estimated that ~25% of CRC patients have synchronous metastases at diagnosis, and about 60% of CRC patients will develop metastases during the follow up. Although several teams have performed simultaneous laparoscopic resec...

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Autores principales:	Giuseppe Sena, Arcangelo Picciariello, Fabio Marino, Marta Goglia, Aldo Rocca, Roberto L. Meniconi, Gaetano Gallo
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	colorectal cancer liver synchronous metastasis simultaneous laparoscopic resection outcomes timing one stage treatment Surgery RD1-811
Acceso en línea:	https://doaj.org/article/35ad9bbf368b4074bd82b995fdf6aa43
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spelling	oai:doaj.org-article:35ad9bbf368b4074bd82b995fdf6aa432021-11-18T09:18:34ZOne-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?2296-875X10.3389/fsurg.2021.752135https://doaj.org/article/35ad9bbf368b4074bd82b995fdf6aa432021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fsurg.2021.752135/fullhttps://doaj.org/toc/2296-875XLiver is the main target organ for colorectal cancer (CRC) metastases. It is estimated that ~25% of CRC patients have synchronous metastases at diagnosis, and about 60% of CRC patients will develop metastases during the follow up. Although several teams have performed simultaneous laparoscopic resections (SLR) of liver and colorectal lesions, the feasibility and safety of this approach is still widely debated and few studies on this topic are present in the literature. The purpose of this literature review is to understand the state of the art of SLR and to clarify the potential benefits and limitations of this approach. Several studies have shown that SLR can be performed safely and with short-term outcomes similarly to the separated procedures. Simultaneous laparoscopic colorectal and hepatic resections combine the advantages of one stage surgery with those of laparoscopic surgery. Several reports compared the short-term outcomes of one stage laparoscopic resection with open resections and showed a similar or inferior amount of blood loss, a similar or lower complication rate, and a significant reduction of hospital stay for laparoscopic surgery respect to open surgery but much longer operating times for the laparoscopic technique. Few retrospective studies compared long term outcomes of laparoscopic one stage surgery with the outcomes of open one stage surgery and did not identify any differences about disease free survival and the overall survival. In conclusion, hepatic and colorectal SLR are a safe and effective approach characterized by less intraoperative blood loss, faster recovery of intestinal function, and shorter length of postoperative hospital stay. Moreover, laparoscopic approach is associated to lower rates of surgical complications without significant differences in the long-term outcomes compared to the open surgery.Giuseppe SenaArcangelo PicciarielloFabio MarinoMarta GogliaAldo RoccaRoberto L. MeniconiGaetano GalloFrontiers Media S.A.articlecolorectal cancerliver synchronous metastasissimultaneous laparoscopic resectionoutcomestimingone stage treatmentSurgeryRD1-811ENFrontiers in Surgery, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	colorectal cancer liver synchronous metastasis simultaneous laparoscopic resection outcomes timing one stage treatment Surgery RD1-811
spellingShingle	colorectal cancer liver synchronous metastasis simultaneous laparoscopic resection outcomes timing one stage treatment Surgery RD1-811 Giuseppe Sena Arcangelo Picciariello Fabio Marino Marta Goglia Aldo Rocca Roberto L. Meniconi Gaetano Gallo One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
description	Liver is the main target organ for colorectal cancer (CRC) metastases. It is estimated that ~25% of CRC patients have synchronous metastases at diagnosis, and about 60% of CRC patients will develop metastases during the follow up. Although several teams have performed simultaneous laparoscopic resections (SLR) of liver and colorectal lesions, the feasibility and safety of this approach is still widely debated and few studies on this topic are present in the literature. The purpose of this literature review is to understand the state of the art of SLR and to clarify the potential benefits and limitations of this approach. Several studies have shown that SLR can be performed safely and with short-term outcomes similarly to the separated procedures. Simultaneous laparoscopic colorectal and hepatic resections combine the advantages of one stage surgery with those of laparoscopic surgery. Several reports compared the short-term outcomes of one stage laparoscopic resection with open resections and showed a similar or inferior amount of blood loss, a similar or lower complication rate, and a significant reduction of hospital stay for laparoscopic surgery respect to open surgery but much longer operating times for the laparoscopic technique. Few retrospective studies compared long term outcomes of laparoscopic one stage surgery with the outcomes of open one stage surgery and did not identify any differences about disease free survival and the overall survival. In conclusion, hepatic and colorectal SLR are a safe and effective approach characterized by less intraoperative blood loss, faster recovery of intestinal function, and shorter length of postoperative hospital stay. Moreover, laparoscopic approach is associated to lower rates of surgical complications without significant differences in the long-term outcomes compared to the open surgery.
format	article
author	Giuseppe Sena Arcangelo Picciariello Fabio Marino Marta Goglia Aldo Rocca Roberto L. Meniconi Gaetano Gallo
author_facet	Giuseppe Sena Arcangelo Picciariello Fabio Marino Marta Goglia Aldo Rocca Roberto L. Meniconi Gaetano Gallo
author_sort	Giuseppe Sena
title	One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
title_short	One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
title_full	One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
title_fullStr	One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
title_full_unstemmed	One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?
title_sort	one-stage total laparoscopic treatment for colorectal cancer with synchronous metastasis. is it safe and feasible?
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/35ad9bbf368b4074bd82b995fdf6aa43
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One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?

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