Chemogenetic ON and OFF switches for RNA virus replication

Chemogenetic ON and OFF switches for RNA virus replication

Therapeutic application of RNA viruses requires tight control over viral activity. Here the authors design a regulatory switch that enables control over activity with clinically approved HIV protease inhibitors.

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Auteurs principaux: E. Heilmann, J. Kimpel, B. Hofer, A. Rössler, I. Blaas, L. Egerer, T. Nolden, C. Urbiola, H. G. Kräusslich, G. Wollmann, D. von Laer
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Science
Q
Accès en ligne:https://doaj.org/article/35bc65b4fdf149b39015ce63f7540b25
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Résumé:Therapeutic application of RNA viruses requires tight control over viral activity. Here the authors design a regulatory switch that enables control over activity with clinically approved HIV protease inhibitors.

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