Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.
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Nature Portfolio
2018
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oai:doaj.org-article:35be9cbfd9d943158a629a540eb68b222021-12-02T14:41:28ZCharacterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients10.1038/s41467-018-03867-92041-1723https://doaj.org/article/35be9cbfd9d943158a629a540eb68b222018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03867-9https://doaj.org/toc/2041-1723The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.Li ChenLiu YangLing YaoXia-Ying KuangWen-Jia ZuoShan LiFeng QiaoYi-Rong LiuZhi-Gang CaoShu-Ling ZhouXiao-Yan ZhouWen-Tao YangJin-Xiu ShiWei HuangXin HuZhi-Ming ShaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
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Science Q |
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Science Q Li Chen Liu Yang Ling Yao Xia-Ying Kuang Wen-Jia Zuo Shan Li Feng Qiao Yi-Rong Liu Zhi-Gang Cao Shu-Ling Zhou Xiao-Yan Zhou Wen-Tao Yang Jin-Xiu Shi Wei Huang Xin Hu Zhi-Ming Shao Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
description |
The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China. |
format |
article |
author |
Li Chen Liu Yang Ling Yao Xia-Ying Kuang Wen-Jia Zuo Shan Li Feng Qiao Yi-Rong Liu Zhi-Gang Cao Shu-Ling Zhou Xiao-Yan Zhou Wen-Tao Yang Jin-Xiu Shi Wei Huang Xin Hu Zhi-Ming Shao |
author_facet |
Li Chen Liu Yang Ling Yao Xia-Ying Kuang Wen-Jia Zuo Shan Li Feng Qiao Yi-Rong Liu Zhi-Gang Cao Shu-Ling Zhou Xiao-Yan Zhou Wen-Tao Yang Jin-Xiu Shi Wei Huang Xin Hu Zhi-Ming Shao |
author_sort |
Li Chen |
title |
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
title_short |
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
title_full |
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
title_fullStr |
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
title_full_unstemmed |
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients |
title_sort |
characterization of pik3ca and pik3r1 somatic mutations in chinese breast cancer patients |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/35be9cbfd9d943158a629a540eb68b22 |
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