Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients

The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.

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Autores principales: Li Chen, Liu Yang, Ling Yao, Xia-Ying Kuang, Wen-Jia Zuo, Shan Li, Feng Qiao, Yi-Rong Liu, Zhi-Gang Cao, Shu-Ling Zhou, Xiao-Yan Zhou, Wen-Tao Yang, Jin-Xiu Shi, Wei Huang, Xin Hu, Zhi-Ming Shao
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/35be9cbfd9d943158a629a540eb68b22
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spelling oai:doaj.org-article:35be9cbfd9d943158a629a540eb68b222021-12-02T14:41:28ZCharacterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients10.1038/s41467-018-03867-92041-1723https://doaj.org/article/35be9cbfd9d943158a629a540eb68b222018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03867-9https://doaj.org/toc/2041-1723The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.Li ChenLiu YangLing YaoXia-Ying KuangWen-Jia ZuoShan LiFeng QiaoYi-Rong LiuZhi-Gang CaoShu-Ling ZhouXiao-Yan ZhouWen-Tao YangJin-Xiu ShiWei HuangXin HuZhi-Ming ShaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Li Chen
Liu Yang
Ling Yao
Xia-Ying Kuang
Wen-Jia Zuo
Shan Li
Feng Qiao
Yi-Rong Liu
Zhi-Gang Cao
Shu-Ling Zhou
Xiao-Yan Zhou
Wen-Tao Yang
Jin-Xiu Shi
Wei Huang
Xin Hu
Zhi-Ming Shao
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
description The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.
format article
author Li Chen
Liu Yang
Ling Yao
Xia-Ying Kuang
Wen-Jia Zuo
Shan Li
Feng Qiao
Yi-Rong Liu
Zhi-Gang Cao
Shu-Ling Zhou
Xiao-Yan Zhou
Wen-Tao Yang
Jin-Xiu Shi
Wei Huang
Xin Hu
Zhi-Ming Shao
author_facet Li Chen
Liu Yang
Ling Yao
Xia-Ying Kuang
Wen-Jia Zuo
Shan Li
Feng Qiao
Yi-Rong Liu
Zhi-Gang Cao
Shu-Ling Zhou
Xiao-Yan Zhou
Wen-Tao Yang
Jin-Xiu Shi
Wei Huang
Xin Hu
Zhi-Ming Shao
author_sort Li Chen
title Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
title_short Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
title_full Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
title_fullStr Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
title_full_unstemmed Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
title_sort characterization of pik3ca and pik3r1 somatic mutations in chinese breast cancer patients
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/35be9cbfd9d943158a629a540eb68b22
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