Brinzolamide-timolol suspension: acceptability and side effect profile

MD Doherty, SG Fraser, PS PhelanSunderland Eye Infirmary, Sunderland, Tyne and Wear, UKBackground: This study aimed to determine the frequency, nature, and impact of side effects associated with the use of brinzolamide-timolol suspension, a topical ocular antihypertensive preparation.Methods: A ques...

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Autores principales:	Doherty MD, Fraser SG, Phelan PS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/35c44b76edd847e5b088353985bb05c7
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spelling	oai:doaj.org-article:35c44b76edd847e5b088353985bb05c72021-12-02T08:49:25ZBrinzolamide-timolol suspension: acceptability and side effect profile1177-54671177-5483https://doaj.org/article/35c44b76edd847e5b088353985bb05c72011-03-01T00:00:00Zhttp://www.dovepress.com/brinzolamide-timolol-suspension-acceptability-and-side-effect-profile-a6911https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483MD Doherty, SG Fraser, PS PhelanSunderland Eye Infirmary, Sunderland, Tyne and Wear, UKBackground: This study aimed to determine the frequency, nature, and impact of side effects associated with the use of brinzolamide-timolol suspension, a topical ocular antihypertensive preparation.Methods: A questionnaire was distributed to 76 consecutive patients attending the Sunderland Eye Infirmary Glaucoma Service who were using the brinzolamide-timolol suspension. The questions related specifically to effects on daily life, blurring of vision, stinging, irritation, and acceptability compared with any drops previously used. Respondents were asked to grade their answers to these questions using a numerical scale from 0 to 10.Results: Seventy-six patients (100%) responded, comprising 58 females and 18 males, aged 68&ndash;95 years, treated for 3&ndash;7 months. Quality of life was not significantly affected, with the majority of patients recording a response between 0 and 2. Visual blurring was a more prominent feature, with the most common scores being 3 and 4. Stinging did not appear to be a prominent feature, with 0 as the most common response. Similarly, irritation was not a common finding, with most respondents scoring 0 and 1. Finally, the brinzolamide-timolol suspension compared favorably with previously used drops, with the vast majority of patients expressing a preference for this suspension over other topical medications.Conclusion: Brinzolamide-timolol suspension appears to be a well tolerated and acceptable medication, with minimal effect on patient quality of life.Keywords: intraocular pressure, glaucoma, quality of life, side effects Doherty MDFraser SGPhelan PSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 419-423 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Doherty MD Fraser SG Phelan PS Brinzolamide-timolol suspension: acceptability and side effect profile
description	MD Doherty, SG Fraser, PS PhelanSunderland Eye Infirmary, Sunderland, Tyne and Wear, UKBackground: This study aimed to determine the frequency, nature, and impact of side effects associated with the use of brinzolamide-timolol suspension, a topical ocular antihypertensive preparation.Methods: A questionnaire was distributed to 76 consecutive patients attending the Sunderland Eye Infirmary Glaucoma Service who were using the brinzolamide-timolol suspension. The questions related specifically to effects on daily life, blurring of vision, stinging, irritation, and acceptability compared with any drops previously used. Respondents were asked to grade their answers to these questions using a numerical scale from 0 to 10.Results: Seventy-six patients (100%) responded, comprising 58 females and 18 males, aged 68&ndash;95 years, treated for 3&ndash;7 months. Quality of life was not significantly affected, with the majority of patients recording a response between 0 and 2. Visual blurring was a more prominent feature, with the most common scores being 3 and 4. Stinging did not appear to be a prominent feature, with 0 as the most common response. Similarly, irritation was not a common finding, with most respondents scoring 0 and 1. Finally, the brinzolamide-timolol suspension compared favorably with previously used drops, with the vast majority of patients expressing a preference for this suspension over other topical medications.Conclusion: Brinzolamide-timolol suspension appears to be a well tolerated and acceptable medication, with minimal effect on patient quality of life.Keywords: intraocular pressure, glaucoma, quality of life, side effects
format	article
author	Doherty MD Fraser SG Phelan PS
author_facet	Doherty MD Fraser SG Phelan PS
author_sort	Doherty MD
title	Brinzolamide-timolol suspension: acceptability and side effect profile
title_short	Brinzolamide-timolol suspension: acceptability and side effect profile
title_full	Brinzolamide-timolol suspension: acceptability and side effect profile
title_fullStr	Brinzolamide-timolol suspension: acceptability and side effect profile
title_full_unstemmed	Brinzolamide-timolol suspension: acceptability and side effect profile
title_sort	brinzolamide-timolol suspension: acceptability and side effect profile
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/35c44b76edd847e5b088353985bb05c7
work_keys_str_mv	AT dohertymd brinzolamidetimololsuspensionacceptabilityandsideeffectprofile AT frasersg brinzolamidetimololsuspensionacceptabilityandsideeffectprofile AT phelanps brinzolamidetimololsuspensionacceptabilityandsideeffectprofile
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Brinzolamide-timolol suspension: acceptability and side effect profile

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