Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates
Rania Serag Elkitkat,1– 3 Yousef A Fouad,1 Abdelrhman Shams,1 Ismail Hamza1 1Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt; 2Watany Eye Hospital, Cairo, Egypt; 3Watany Research and Development Center, Cairo, EgyptCorrespondence: Abdelrhman ShamsFaculty o...
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oai:doaj.org-article:35c4e43f972546c1a6068b9ba26258622021-12-02T11:56:35ZNormative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates1177-5483https://doaj.org/article/35c4e43f972546c1a6068b9ba26258622020-12-01T00:00:00Zhttps://www.dovepress.com/normative-values-of-corneal-spherical-aberration-pupil-size-and-other--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Rania Serag Elkitkat,1– 3 Yousef A Fouad,1 Abdelrhman Shams,1 Ismail Hamza1 1Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt; 2Watany Eye Hospital, Cairo, Egypt; 3Watany Research and Development Center, Cairo, EgyptCorrespondence: Abdelrhman ShamsFaculty of Medicine, Ain Shams University, Cairo, EgyptTel +201222131012Email abdelrhmanshams@hotmail.comPurpose: To determine the spherical aberration, pupil size, and other key refractive and topographic parameters in a large cohort of Egyptian cataract surgery candidates, and to investigate any existent relations between the spherical aberration and other possibly related parameters.Methods: This is a cross-sectional, descriptive study that was conducted at Ain Shams University Hospitals, Cairo, Egypt. The study was performed on the right eyes of 1658 cataract surgery candidates. The mean corneal spherical aberration [Z4] and the pupil diameter, both photopic [P. Pupil] and mesopic [M. Pupil], were measured by the Oculus Keratograph 3, while the white-to-white corneal diameter [WTW], average keratometric readings [average K], axial length measurements [AL] and Anterior Chamber Depth [ACD] were all obtained from the IOL Master 500.Results: The mean age was 65 ± 11.3 years. The mean value of the Z4 was +0.26 ± 0.12 μm [95% Confidence Interval “CI” (0.2570– 0.2681)]. The mean values of the measured parameters were: P. Pupil 2.43 ± 0.87 mm [95% CI (2.3867– 2.4700)], M. Pupil 4.61 ± 0.91 mm [95% CI (4.5683– 4.6557)], WTW 11.72 ± 0.44 mm [95% CI (11.6969– 11.7394)], average K 43.89 ± 1.89 D [95% CI (43.7938– 43.9701)], AL 24.23 ± 2.21 mm [95% CI (24.1118– 24.3166)], and ACD 3.16 ± 0.43 mm [95% CI (3.1414– 3.1827)]. Weak statistically significant correlations were found between the Z4 and each of age (r = 0.049, p = 0.044), average K (r = 0.191, p < 0.001), and ACD (r = 0.122, p < 0.001). Multivariate analysis showed weaker relations between Z4 and both average K (beta coefficient= 0.091) and ACD (beta coefficient= 0.130), with an r2 = 0.024.Conclusion: This is the first normative data report of corneal spherical aberration [Z4], pupil size, and related refractive and topographic parameters in an old Egyptian population. The detected correlations have a weak clinical relevance and negate the existence of significant relations between the Z4 and the studied refractive and topographic parameters.Keywords: corneal spherical aberration, Z4, corneal keratography, white-to-white corneal diameter, Egyptian populationElkitkat RSFouad YAShams AHamza IDove Medical Pressarticlecorneal spherical aberrationz4corneal keratographywhite to white corneal diameteregyptian population.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 4571-4577 (2020) |
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corneal spherical aberration z4 corneal keratography white to white corneal diameter egyptian population. Ophthalmology RE1-994 |
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corneal spherical aberration z4 corneal keratography white to white corneal diameter egyptian population. Ophthalmology RE1-994 Elkitkat RS Fouad YA Shams A Hamza I Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
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Rania Serag Elkitkat,1– 3 Yousef A Fouad,1 Abdelrhman Shams,1 Ismail Hamza1 1Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt; 2Watany Eye Hospital, Cairo, Egypt; 3Watany Research and Development Center, Cairo, EgyptCorrespondence: Abdelrhman ShamsFaculty of Medicine, Ain Shams University, Cairo, EgyptTel +201222131012Email abdelrhmanshams@hotmail.comPurpose: To determine the spherical aberration, pupil size, and other key refractive and topographic parameters in a large cohort of Egyptian cataract surgery candidates, and to investigate any existent relations between the spherical aberration and other possibly related parameters.Methods: This is a cross-sectional, descriptive study that was conducted at Ain Shams University Hospitals, Cairo, Egypt. The study was performed on the right eyes of 1658 cataract surgery candidates. The mean corneal spherical aberration [Z4] and the pupil diameter, both photopic [P. Pupil] and mesopic [M. Pupil], were measured by the Oculus Keratograph 3, while the white-to-white corneal diameter [WTW], average keratometric readings [average K], axial length measurements [AL] and Anterior Chamber Depth [ACD] were all obtained from the IOL Master 500.Results: The mean age was 65 ± 11.3 years. The mean value of the Z4 was +0.26 ± 0.12 μm [95% Confidence Interval “CI” (0.2570– 0.2681)]. The mean values of the measured parameters were: P. Pupil 2.43 ± 0.87 mm [95% CI (2.3867– 2.4700)], M. Pupil 4.61 ± 0.91 mm [95% CI (4.5683– 4.6557)], WTW 11.72 ± 0.44 mm [95% CI (11.6969– 11.7394)], average K 43.89 ± 1.89 D [95% CI (43.7938– 43.9701)], AL 24.23 ± 2.21 mm [95% CI (24.1118– 24.3166)], and ACD 3.16 ± 0.43 mm [95% CI (3.1414– 3.1827)]. Weak statistically significant correlations were found between the Z4 and each of age (r = 0.049, p = 0.044), average K (r = 0.191, p < 0.001), and ACD (r = 0.122, p < 0.001). Multivariate analysis showed weaker relations between Z4 and both average K (beta coefficient= 0.091) and ACD (beta coefficient= 0.130), with an r2 = 0.024.Conclusion: This is the first normative data report of corneal spherical aberration [Z4], pupil size, and related refractive and topographic parameters in an old Egyptian population. The detected correlations have a weak clinical relevance and negate the existence of significant relations between the Z4 and the studied refractive and topographic parameters.Keywords: corneal spherical aberration, Z4, corneal keratography, white-to-white corneal diameter, Egyptian population |
format |
article |
author |
Elkitkat RS Fouad YA Shams A Hamza I |
author_facet |
Elkitkat RS Fouad YA Shams A Hamza I |
author_sort |
Elkitkat RS |
title |
Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
title_short |
Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
title_full |
Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
title_fullStr |
Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
title_full_unstemmed |
Normative Values of Corneal Spherical Aberration, Pupil Size, and Other Key Refractive and Topographic Parameters in a Large Cohort of Egyptian Cataract Surgery Candidates |
title_sort |
normative values of corneal spherical aberration, pupil size, and other key refractive and topographic parameters in a large cohort of egyptian cataract surgery candidates |
publisher |
Dove Medical Press |
publishDate |
2020 |
url |
https://doaj.org/article/35c4e43f972546c1a6068b9ba2625862 |
work_keys_str_mv |
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