Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Diana Langer, Igor Martianov, Daniel Alpern, Muriel Rhinn, Céline Keime, Pascal Dollé, Gabrielle Mengus, Irwin Davidson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/35c63257ca0b40aba3201b666e21f6ba
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:35c63257ca0b40aba3201b666e21f6ba
record_format	dspace
spelling	oai:doaj.org-article:35c63257ca0b40aba3201b666e21f6ba2021-12-02T14:39:12ZEssential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation10.1038/ncomms110632041-1723https://doaj.org/article/35c63257ca0b40aba3201b666e21f6ba2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11063https://doaj.org/toc/2041-1723The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages.Diana LangerIgor MartianovDaniel AlpernMuriel RhinnCéline KeimePascal DolléGabrielle MengusIrwin DavidsonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diana Langer Igor Martianov Daniel Alpern Muriel Rhinn Céline Keime Pascal Dollé Gabrielle Mengus Irwin Davidson Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
description	The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages.
format	article
author	Diana Langer Igor Martianov Daniel Alpern Muriel Rhinn Céline Keime Pascal Dollé Gabrielle Mengus Irwin Davidson
author_facet	Diana Langer Igor Martianov Daniel Alpern Muriel Rhinn Céline Keime Pascal Dollé Gabrielle Mengus Irwin Davidson
author_sort	Diana Langer
title	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
title_short	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
title_full	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
title_fullStr	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
title_full_unstemmed	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
title_sort	essential role of the tfiid subunit taf4 in murine embryogenesis and embryonic stem cell differentiation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/35c63257ca0b40aba3201b666e21f6ba
work_keys_str_mv	AT dianalanger essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT igormartianov essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT danielalpern essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT murielrhinn essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT celinekeime essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT pascaldolle essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT gabriellemengus essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation AT irwindavidson essentialroleofthetfiidsubunittaf4inmurineembryogenesisandembryonicstemcelldifferentiation
_version_	1718390707354337280

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

Ejemplares similares