Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages...

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Autores principales: Diana Langer, Igor Martianov, Daniel Alpern, Muriel Rhinn, Céline Keime, Pascal Dollé, Gabrielle Mengus, Irwin Davidson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/35c63257ca0b40aba3201b666e21f6ba
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