Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents

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Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents

Summary: The anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2C receptors (Htr2cs). Using mouse genetic models in which Htr2c can be selectively deleted or restored (in Htr2c-null mice), we investigate the role of Htr2c in forebrain Sim1 neurons....

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Détails bibliographiques
Auteurs principaux:	Eun-Seon Yoo, Li Li, Lin Jia, Caleb C. Lord, Charlotte E. Lee, Shari G. Birnbaum, Claudia R. Vianna, Eric D. Berglund, Kathryn A. Cunningham, Yong Xu, Jong-Woo Sohn, Chen Liu
Format:	article
Langue:	EN
Publié:	Elsevier 2021
Sujets:	Htr2c feeding obesity KATP lorcaserin hypothalamus Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/35dc83b9b582460d887dc765f85d34a0
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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