Identification of significantly mutated subnetworks in the breast cancer genome
Abstract Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this r...
Enregistré dans:
Auteurs principaux: | Rasif Ajwad, Michael Domaratzki, Qian Liu, Nikta Feizi, Pingzhao Hu |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/35eb7bde4a5b4476838f5f4ffa421d0f |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Drug repositioning by merging active subnetworks validated in cancer and COVID-19
par: Marta Lucchetta, et autres
Publié: (2021) -
The relative timing of mutations in a breast cancer genome.
par: Scott Newman, et autres
Publié: (2013) -
Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients
par: Axel Muendlein, et autres
Publié: (2021) -
The topography of mutational processes in breast cancer genomes
par: Sandro Morganella, et autres
Publié: (2016) -
Genetic Pathways and Functional Subnetworks for the Complex Nature of Bipolar Disorder in Genome-Wide Association Study
par: Chan-Yen Kuo, et autres
Publié: (2021)