Identification of significantly mutated subnetworks in the breast cancer genome

Abstract Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this r...

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Bibliographic Details
Main Authors: Rasif Ajwad, Michael Domaratzki, Qian Liu, Nikta Feizi, Pingzhao Hu
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/35eb7bde4a5b4476838f5f4ffa421d0f
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