A stem cell journey in ophthalmology: From the bench to the clinic

Abstract Debilitating diseases of the eye represent a large unmet medical need potentially addressable with stem cell‐based approaches. Over the past decade, the California Institute for Regenerative Medicine (CIRM) has funded and supported the translation, from early research concepts to human tria...

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Autores principales:	Ingrid W. Caras, Lila R. Collins, Abla A. Creasey
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	cellular therapy clinical translation retina retinal pigmented epithelium stem cells Medicine (General) R5-920 Cytology QH573-671
Acceso en línea:	https://doaj.org/article/35fde565978d47d99ce00268f90fa6f0
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id	oai:doaj.org-article:35fde565978d47d99ce00268f90fa6f0
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spelling	oai:doaj.org-article:35fde565978d47d99ce00268f90fa6f02021-12-03T12:11:46ZA stem cell journey in ophthalmology: From the bench to the clinic2157-65802157-656410.1002/sctm.21-0239https://doaj.org/article/35fde565978d47d99ce00268f90fa6f02021-12-01T00:00:00Zhttps://doi.org/10.1002/sctm.21-0239https://doaj.org/toc/2157-6564https://doaj.org/toc/2157-6580Abstract Debilitating diseases of the eye represent a large unmet medical need potentially addressable with stem cell‐based approaches. Over the past decade, the California Institute for Regenerative Medicine (CIRM) has funded and supported the translation, from early research concepts to human trials, of therapeutic stem cell approaches for dry age‐related macular degeneration, retinitis pigmentosa, and limbal stem cell deficiency. This article chronicles CIRM's journey in the ophthalmology field and discusses some key challenges and questions that were addressed along the way as well as questions that remain.Ingrid W. CarasLila R. CollinsAbla A. CreaseyWileyarticlecellular therapyclinical translationretinaretinal pigmented epitheliumstem cellsMedicine (General)R5-920CytologyQH573-671ENStem Cells Translational Medicine, Vol 10, Iss 12, Pp 1581-1587 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cellular therapy clinical translation retina retinal pigmented epithelium stem cells Medicine (General) R5-920 Cytology QH573-671
spellingShingle	cellular therapy clinical translation retina retinal pigmented epithelium stem cells Medicine (General) R5-920 Cytology QH573-671 Ingrid W. Caras Lila R. Collins Abla A. Creasey A stem cell journey in ophthalmology: From the bench to the clinic
description	Abstract Debilitating diseases of the eye represent a large unmet medical need potentially addressable with stem cell‐based approaches. Over the past decade, the California Institute for Regenerative Medicine (CIRM) has funded and supported the translation, from early research concepts to human trials, of therapeutic stem cell approaches for dry age‐related macular degeneration, retinitis pigmentosa, and limbal stem cell deficiency. This article chronicles CIRM's journey in the ophthalmology field and discusses some key challenges and questions that were addressed along the way as well as questions that remain.
format	article
author	Ingrid W. Caras Lila R. Collins Abla A. Creasey
author_facet	Ingrid W. Caras Lila R. Collins Abla A. Creasey
author_sort	Ingrid W. Caras
title	A stem cell journey in ophthalmology: From the bench to the clinic
title_short	A stem cell journey in ophthalmology: From the bench to the clinic
title_full	A stem cell journey in ophthalmology: From the bench to the clinic
title_fullStr	A stem cell journey in ophthalmology: From the bench to the clinic
title_full_unstemmed	A stem cell journey in ophthalmology: From the bench to the clinic
title_sort	stem cell journey in ophthalmology: from the bench to the clinic
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/35fde565978d47d99ce00268f90fa6f0
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A stem cell journey in ophthalmology: From the bench to the clinic

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