Stem cell proliferation is induced by apoptotic bodies from dying cells during epithelial tissue maintenance

Damaged epithelial tissues are known to compensate for cell death through compensatory cell divisions to maintain epithelial integrity. Here, the authors show in living epithelia that dying cells stimulate adjacent stem cells to divide through caspase-dependent production of Wnt8a-containing apoptot...

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Auteurs principaux: Courtney K. Brock, Stephen T. Wallin, Oscar E. Ruiz, Krystin M. Samms, Amrita Mandal, Elizabeth A. Sumner, George T. Eisenhoffer
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/36038ed7967345729d64f073b9d12a1c
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