Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device

Background: There has been a steady and consistent rise in the use of left ventricular assist devices in the management of patients with advanced heart failure. Hypothyroidism also remains one of the most common endocrine conditions with a significant impact on the development and overall outcomes o...

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Autores principales:	Sakiru O Isa, Olajide Buhari, Muminat Adeniran-Isa, Nischit Baral, Govinda Adhikari, Basel AbdulAzeem, Pramod Savarapu, Oyebimpe Adekolujo, Mustafa Hassan, Adedayo Adeboye
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/360c5ef374444b16abe99ee06a4d899d
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spelling	oai:doaj.org-article:360c5ef374444b16abe99ee06a4d899d2021-12-05T03:03:26ZHypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device1179-546810.1177/11795468211058761https://doaj.org/article/360c5ef374444b16abe99ee06a4d899d2021-12-01T00:00:00Zhttps://doi.org/10.1177/11795468211058761https://doaj.org/toc/1179-5468Background: There has been a steady and consistent rise in the use of left ventricular assist devices in the management of patients with advanced heart failure. Hypothyroidism also remains one of the most common endocrine conditions with a significant impact on the development and overall outcomes of heart failure. The authors analyzed the National Inpatient Sample to evaluate the effect of hypothyroidism on the in-hospital outcomes of patients with end-stage heart failure following the placement of left ventricular assist device. Methods: The national inpatient sample was queried to identify all adult patients who had LVAD placement from 2004 to 2014. They were subsequently divided into those with hypothyroidism and those without hypothyroidism. The primary outcome was in-hospital mortality. Other outcomes were acute kidney injury, length, and cost of hospitalization. Logistic regression models were created to determine the outcomes of interest. Results: Of 2643 patients in the study, 5.4% had hypothyroidism, and 94.6% did not. The hypothyroid patients were significantly older compared to the non-hypothyroid patients (mean age 58.6 years vs 49.95 years, P -value <.0001). Both groups had similar gender composition. In-hospital mortality was similar across both groups. However, there was a higher incidence of acute kidney injury (AKI) in the hypothyroid group (adjusted odds ratio [aOR 1.83, P -value <.001]). Hypothyroid patients had longer hospital stays (adjusted mean difference [aMD] 5.19, P -value .0001). Hospital charges were also higher in the hypothyroid group. Conclusion: This study found that LVAD is associated with longer hospital stay in hypothyroid patients with heart failure.Sakiru O IsaOlajide BuhariMuminat Adeniran-IsaNischit BaralGovinda AdhikariBasel AbdulAzeemPramod SavarapuOyebimpe AdekolujoMustafa HassanAdedayo AdeboyeSAGE PublishingarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENClinical Medicine Insights: Cardiology, Vol 15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Sakiru O Isa Olajide Buhari Muminat Adeniran-Isa Nischit Baral Govinda Adhikari Basel AbdulAzeem Pramod Savarapu Oyebimpe Adekolujo Mustafa Hassan Adedayo Adeboye Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
description	Background: There has been a steady and consistent rise in the use of left ventricular assist devices in the management of patients with advanced heart failure. Hypothyroidism also remains one of the most common endocrine conditions with a significant impact on the development and overall outcomes of heart failure. The authors analyzed the National Inpatient Sample to evaluate the effect of hypothyroidism on the in-hospital outcomes of patients with end-stage heart failure following the placement of left ventricular assist device. Methods: The national inpatient sample was queried to identify all adult patients who had LVAD placement from 2004 to 2014. They were subsequently divided into those with hypothyroidism and those without hypothyroidism. The primary outcome was in-hospital mortality. Other outcomes were acute kidney injury, length, and cost of hospitalization. Logistic regression models were created to determine the outcomes of interest. Results: Of 2643 patients in the study, 5.4% had hypothyroidism, and 94.6% did not. The hypothyroid patients were significantly older compared to the non-hypothyroid patients (mean age 58.6 years vs 49.95 years, P -value <.0001). Both groups had similar gender composition. In-hospital mortality was similar across both groups. However, there was a higher incidence of acute kidney injury (AKI) in the hypothyroid group (adjusted odds ratio [aOR 1.83, P -value <.001]). Hypothyroid patients had longer hospital stays (adjusted mean difference [aMD] 5.19, P -value .0001). Hospital charges were also higher in the hypothyroid group. Conclusion: This study found that LVAD is associated with longer hospital stay in hypothyroid patients with heart failure.
format	article
author	Sakiru O Isa Olajide Buhari Muminat Adeniran-Isa Nischit Baral Govinda Adhikari Basel AbdulAzeem Pramod Savarapu Oyebimpe Adekolujo Mustafa Hassan Adedayo Adeboye
author_facet	Sakiru O Isa Olajide Buhari Muminat Adeniran-Isa Nischit Baral Govinda Adhikari Basel AbdulAzeem Pramod Savarapu Oyebimpe Adekolujo Mustafa Hassan Adedayo Adeboye
author_sort	Sakiru O Isa
title	Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
title_short	Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
title_full	Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
title_fullStr	Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
title_full_unstemmed	Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device
title_sort	hypothyroidism is associated with longer hospital stay following implantation of left ventricular assist device
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/360c5ef374444b16abe99ee06a4d899d
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Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device

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