The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions

Objective: Glycolated Hb is a valuable marker for identification and treatment of diabetics. It shows the mean of blood glucose level during the last 2-3 months. There are different methods (Electrophoresis, colorimetry, …) for evaluation of this indicator with advantages or disadvantages for each....

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Autores principales:	H Alaoddolei, J Vahab Zanjani, F Sadighian
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2000
Materias:	diabetes glycolated hemoglobin hba<sub>1c</sub> hba<sub>1</sub> Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/360e8e65ec8448c78b8ec87849804a77
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id	oai:doaj.org-article:360e8e65ec8448c78b8ec87849804a77
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spelling	oai:doaj.org-article:360e8e65ec8448c78b8ec87849804a772021-11-10T09:22:21ZThe comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions1561-41072251-7170https://doaj.org/article/360e8e65ec8448c78b8ec87849804a772000-10-01T00:00:00Zhttp://jbums.org/article-1-2894-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Glycolated Hb is a valuable marker for identification and treatment of diabetics. It shows the mean of blood glucose level during the last 2-3 months. There are different methods (Electrophoresis, colorimetry, …) for evaluation of this indicator with advantages or disadvantages for each. Methods: This is a descriptive-analytical study that was done on patients referred to Shahid Beheshti hospital in Babol with their fasting blood samples collected. Also 30 persons were selected for evaluation of two methods (Electrophoresis and colorimetry) of measurement of glycolated Hb in fasting and non-fasting conditions. Findings: Mean of GHb by electrophoresis in fasting was 10.01% and in non-fasting was 11.04%. This marker by colorimetric method in fasting and non-fasting was 362.4 and 361.5 nmol/gHb respectively. The difference of GHb by electrophoresis between fasting and non-fasting conditions was significantly (P<0.001), but for colorimetry was significant. Conclusion: GHb is a good marker of the mean value of glucose level for the recent 2-3 months of the individuals. Electrophoresis is a simple method, but regarding the findings taking the samples infasting is strictly recommended. Colorimetric method had not been influenced by the level of glucose at the time of sampling. But this method must be calibrated well.H AlaoddoleiJ Vahab ZanjaniF SadighianBabol University of Medical Sciencesarticlediabetesglycolated hemoglobinhba<sub>1c</sub>hba<sub>1</sub>MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 2, Iss 4, Pp 41-45 (2000)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	diabetes glycolated hemoglobin hba<sub>1c</sub> hba<sub>1</sub> Medicine R Medicine (General) R5-920
spellingShingle	diabetes glycolated hemoglobin hba<sub>1c</sub> hba<sub>1</sub> Medicine R Medicine (General) R5-920 H Alaoddolei J Vahab Zanjani F Sadighian The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
description	Objective: Glycolated Hb is a valuable marker for identification and treatment of diabetics. It shows the mean of blood glucose level during the last 2-3 months. There are different methods (Electrophoresis, colorimetry, …) for evaluation of this indicator with advantages or disadvantages for each. Methods: This is a descriptive-analytical study that was done on patients referred to Shahid Beheshti hospital in Babol with their fasting blood samples collected. Also 30 persons were selected for evaluation of two methods (Electrophoresis and colorimetry) of measurement of glycolated Hb in fasting and non-fasting conditions. Findings: Mean of GHb by electrophoresis in fasting was 10.01% and in non-fasting was 11.04%. This marker by colorimetric method in fasting and non-fasting was 362.4 and 361.5 nmol/gHb respectively. The difference of GHb by electrophoresis between fasting and non-fasting conditions was significantly (P<0.001), but for colorimetry was significant. Conclusion: GHb is a good marker of the mean value of glucose level for the recent 2-3 months of the individuals. Electrophoresis is a simple method, but regarding the findings taking the samples infasting is strictly recommended. Colorimetric method had not been influenced by the level of glucose at the time of sampling. But this method must be calibrated well.
format	article
author	H Alaoddolei J Vahab Zanjani F Sadighian
author_facet	H Alaoddolei J Vahab Zanjani F Sadighian
author_sort	H Alaoddolei
title	The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
title_short	The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
title_full	The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
title_fullStr	The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
title_full_unstemmed	The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions
title_sort	comparison of two measuring methods of glycolated hemoglobin in fasting and non-fasting conditions
publisher	Babol University of Medical Sciences
publishDate	2000
url	https://doaj.org/article/360e8e65ec8448c78b8ec87849804a77
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The comparison of two measuring methods of Glycolated hemoglobin in fasting and non-fasting conditions

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