IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.

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Detalles Bibliográficos
Autores principales: Olga Babaev, Hugo Cruces-Solis, Carolina Piletti Chatain, Matthieu Hammer, Sally Wenger, Heba Ali, Nikolaos Karalis, Livia de Hoz, Oliver M. Schlüter, Yuchio Yanagawa, Hannelore Ehrenreich, Holger Taschenberger, Nils Brose, Dilja Krueger-Burg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/362f3b269d1245b2923fe26c721003ee
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Descripción
Sumario:IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.

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