IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.

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Autores principales: Olga Babaev, Hugo Cruces-Solis, Carolina Piletti Chatain, Matthieu Hammer, Sally Wenger, Heba Ali, Nikolaos Karalis, Livia de Hoz, Oliver M. Schlüter, Yuchio Yanagawa, Hannelore Ehrenreich, Holger Taschenberger, Nils Brose, Dilja Krueger-Burg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/362f3b269d1245b2923fe26c721003ee
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spelling oai:doaj.org-article:362f3b269d1245b2923fe26c721003ee2021-12-02T17:32:33ZIgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses10.1038/s41467-018-07762-12041-1723https://doaj.org/article/362f3b269d1245b2923fe26c721003ee2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07762-1https://doaj.org/toc/2041-1723IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.Olga BabaevHugo Cruces-SolisCarolina Piletti ChatainMatthieu HammerSally WengerHeba AliNikolaos KaralisLivia de HozOliver M. SchlüterYuchio YanagawaHannelore EhrenreichHolger TaschenbergerNils BroseDilja Krueger-BurgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Olga Babaev
Hugo Cruces-Solis
Carolina Piletti Chatain
Matthieu Hammer
Sally Wenger
Heba Ali
Nikolaos Karalis
Livia de Hoz
Oliver M. Schlüter
Yuchio Yanagawa
Hannelore Ehrenreich
Holger Taschenberger
Nils Brose
Dilja Krueger-Burg
IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
description IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.
format article
author Olga Babaev
Hugo Cruces-Solis
Carolina Piletti Chatain
Matthieu Hammer
Sally Wenger
Heba Ali
Nikolaos Karalis
Livia de Hoz
Oliver M. Schlüter
Yuchio Yanagawa
Hannelore Ehrenreich
Holger Taschenberger
Nils Brose
Dilja Krueger-Burg
author_facet Olga Babaev
Hugo Cruces-Solis
Carolina Piletti Chatain
Matthieu Hammer
Sally Wenger
Heba Ali
Nikolaos Karalis
Livia de Hoz
Oliver M. Schlüter
Yuchio Yanagawa
Hannelore Ehrenreich
Holger Taschenberger
Nils Brose
Dilja Krueger-Burg
author_sort Olga Babaev
title IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
title_short IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
title_full IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
title_fullStr IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
title_full_unstemmed IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
title_sort igsf9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/362f3b269d1245b2923fe26c721003ee
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