Unilateral vestibular loss impairs external space representation.

The vestibular system is responsible for a wide range of postural and oculomotor functions and maintains an internal, updated representation of the position and movement of the head in space. In this study, we assessed whether unilateral vestibular loss affects external space representation. Patient...

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Autores principales:	Liliane Borel, Christine Redon-Zouiteni, Pierre Cauvin, Michel Dumitrescu, Arnaud Devèze, Jacques Magnan, Patrick Péruch
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/363b87ea93dd4289bbb748ea69a52ec8
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spelling	oai:doaj.org-article:363b87ea93dd4289bbb748ea69a52ec82021-11-18T08:32:57ZUnilateral vestibular loss impairs external space representation.1932-620310.1371/journal.pone.0088576https://doaj.org/article/363b87ea93dd4289bbb748ea69a52ec82014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24523916/?tool=EBIhttps://doaj.org/toc/1932-6203The vestibular system is responsible for a wide range of postural and oculomotor functions and maintains an internal, updated representation of the position and movement of the head in space. In this study, we assessed whether unilateral vestibular loss affects external space representation. Patients with Menière's disease and healthy participants were instructed to point to memorized targets in near (peripersonal) and far (extrapersonal) spaces in the absence or presence of a visual background. These individuals were also required to estimate their body pointing direction. Menière's disease patients were tested before unilateral vestibular neurotomy and during the recovery period (one week and one month after the operation), and healthy participants were tested at similar times. Unilateral vestibular loss impaired the representation of both the external space and the body pointing direction: in the dark, the configuration of perceived targets was shifted toward the lesioned side and compressed toward the contralesioned hemifield, with higher pointing error in the near space. Performance varied according to the time elapsed after neurotomy: deficits were stronger during the early stages, while gradual compensation occurred subsequently. These findings provide the first demonstration of the critical role of vestibular signals in the representation of external space and of body pointing direction in the early stages after unilateral vestibular loss.Liliane BorelChristine Redon-ZouiteniPierre CauvinMichel DumitrescuArnaud DevèzeJacques MagnanPatrick PéruchPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e88576 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Liliane Borel Christine Redon-Zouiteni Pierre Cauvin Michel Dumitrescu Arnaud Devèze Jacques Magnan Patrick Péruch Unilateral vestibular loss impairs external space representation.
description	The vestibular system is responsible for a wide range of postural and oculomotor functions and maintains an internal, updated representation of the position and movement of the head in space. In this study, we assessed whether unilateral vestibular loss affects external space representation. Patients with Menière's disease and healthy participants were instructed to point to memorized targets in near (peripersonal) and far (extrapersonal) spaces in the absence or presence of a visual background. These individuals were also required to estimate their body pointing direction. Menière's disease patients were tested before unilateral vestibular neurotomy and during the recovery period (one week and one month after the operation), and healthy participants were tested at similar times. Unilateral vestibular loss impaired the representation of both the external space and the body pointing direction: in the dark, the configuration of perceived targets was shifted toward the lesioned side and compressed toward the contralesioned hemifield, with higher pointing error in the near space. Performance varied according to the time elapsed after neurotomy: deficits were stronger during the early stages, while gradual compensation occurred subsequently. These findings provide the first demonstration of the critical role of vestibular signals in the representation of external space and of body pointing direction in the early stages after unilateral vestibular loss.
format	article
author	Liliane Borel Christine Redon-Zouiteni Pierre Cauvin Michel Dumitrescu Arnaud Devèze Jacques Magnan Patrick Péruch
author_facet	Liliane Borel Christine Redon-Zouiteni Pierre Cauvin Michel Dumitrescu Arnaud Devèze Jacques Magnan Patrick Péruch
author_sort	Liliane Borel
title	Unilateral vestibular loss impairs external space representation.
title_short	Unilateral vestibular loss impairs external space representation.
title_full	Unilateral vestibular loss impairs external space representation.
title_fullStr	Unilateral vestibular loss impairs external space representation.
title_full_unstemmed	Unilateral vestibular loss impairs external space representation.
title_sort	unilateral vestibular loss impairs external space representation.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/363b87ea93dd4289bbb748ea69a52ec8
work_keys_str_mv	AT lilianeborel unilateralvestibularlossimpairsexternalspacerepresentation AT christineredonzouiteni unilateralvestibularlossimpairsexternalspacerepresentation AT pierrecauvin unilateralvestibularlossimpairsexternalspacerepresentation AT micheldumitrescu unilateralvestibularlossimpairsexternalspacerepresentation AT arnauddeveze unilateralvestibularlossimpairsexternalspacerepresentation AT jacquesmagnan unilateralvestibularlossimpairsexternalspacerepresentation AT patrickperuch unilateralvestibularlossimpairsexternalspacerepresentation
_version_	1718421613311950848

Unilateral vestibular loss impairs external space representation.

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