Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque seminiferous tubules, which matures these int...

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Autores principales:	Enrique Sosa, Di Chen, Ernesto J. Rojas, Jon D. Hennebold, Karen A. Peters, Zhuang Wu, Truong N. Lam, Jennifer M. Mitchell, Meena Sukhwani, Ramesh C. Tailor, Marvin L. Meistrich, Kyle E. Orwig, Gunapala Shetty, Amander T. Clark
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/364bc6a1087149ce821ef0255a15a53c
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spelling	oai:doaj.org-article:364bc6a1087149ce821ef0255a15a53c2021-12-02T17:31:26ZDifferentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche10.1038/s41467-018-07740-72041-1723https://doaj.org/article/364bc6a1087149ce821ef0255a15a53c2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07740-7https://doaj.org/toc/2041-1723Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque seminiferous tubules, which matures these into late PGCs and spermatogonia-like cells.Enrique SosaDi ChenErnesto J. RojasJon D. HenneboldKaren A. PetersZhuang WuTruong N. LamJennifer M. MitchellMeena SukhwaniRamesh C. TailorMarvin L. MeistrichKyle E. OrwigGunapala ShettyAmander T. ClarkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Enrique Sosa Di Chen Ernesto J. Rojas Jon D. Hennebold Karen A. Peters Zhuang Wu Truong N. Lam Jennifer M. Mitchell Meena Sukhwani Ramesh C. Tailor Marvin L. Meistrich Kyle E. Orwig Gunapala Shetty Amander T. Clark Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
description	Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque seminiferous tubules, which matures these into late PGCs and spermatogonia-like cells.
format	article
author	Enrique Sosa Di Chen Ernesto J. Rojas Jon D. Hennebold Karen A. Peters Zhuang Wu Truong N. Lam Jennifer M. Mitchell Meena Sukhwani Ramesh C. Tailor Marvin L. Meistrich Kyle E. Orwig Gunapala Shetty Amander T. Clark
author_facet	Enrique Sosa Di Chen Ernesto J. Rojas Jon D. Hennebold Karen A. Peters Zhuang Wu Truong N. Lam Jennifer M. Mitchell Meena Sukhwani Ramesh C. Tailor Marvin L. Meistrich Kyle E. Orwig Gunapala Shetty Amander T. Clark
author_sort	Enrique Sosa
title	Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
title_short	Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
title_full	Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
title_fullStr	Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
title_full_unstemmed	Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
title_sort	differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/364bc6a1087149ce821ef0255a15a53c
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Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

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