Evaluation of Vitamin D3 level in Sino-nasal Polypi

Background: Vitamin D is a group of fat-soluble corticosteroid responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects. In humans, the most important compounds in this group are vitamin D3 [also known as cholecalciferol] and vitami...

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Autores principales:	Ali Abdel-Rahman, Mahmoud El-Sobky, Amr Rezk, Mohamed Emara
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2019
Materias:	vitamin d3, sino-nasal polypi, chronic rhinosinusitis allergic fungal rhinosinusitis Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3651455b833d41e8a3d330fd0e9cb036
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spelling	oai:doaj.org-article:3651455b833d41e8a3d330fd0e9cb0362021-12-02T15:22:19ZEvaluation of Vitamin D3 level in Sino-nasal Polypi2636-41742682-378010.21608/ijma.2019.17143.1030https://doaj.org/article/3651455b833d41e8a3d330fd0e9cb0362019-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_52878_ea5ce0da1ce13d59339622a8985caa03.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Vitamin D is a group of fat-soluble corticosteroid responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects. In humans, the most important compounds in this group are vitamin D3 [also known as cholecalciferol] and vitamin D2 [ergocalciferol].Aim of the work: The aim of this thesis is to assess Vitamin D3 [VD3] level in patients with sino-nasal polypi in comparison with normal individuals.Patients and Methods: This prospective comparative [case-control] study conducted by the Department of ENT, Al-Azhar University Hospitals in the period from March 2019 to September 2019 and included 40 individuals who were selected by inclusion and exclusion criteria, both genders, all patients had been counseled about the nature of the study and informed written consent has been obtained.Results: Serum level of VD3 in patients with chronic rhinosinusitis with sinonasal polyps [CRSwNP] and allergic fungal rhinosinusitis [AFRS] was significantly lower than that of control subjects. Vitamin D levels ranged from 8.74 to 39 ng/ml, and there was statistically significant decrease of serum vitamin D levels in patient group when compared to control group [16.20±4.29 vs 30.56±4.83 respectively]. In addition, there was significant increase of patients with deficient and insufficient vitamin D levels in patient group when compared to control group.Conclusion: VD3 may constitute an inexpensive prophylactic and cost effective option in the therapeutic armamentarium in reducing inflammation either by itself or as a synergistic agent to traditional agents in patients suffering from sino-nasal polypi.Ali Abdel-RahmanMahmoud El-SobkyAmr RezkMohamed EmaraAl-Azhar University, Faculty of Medicine (Damietta)articlevitamin d3, sino-nasal polypi, chronic rhinosinusitisallergic fungal rhinosinusitisMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 1, Iss 2, Pp 132-137 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	vitamin d3, sino-nasal polypi, chronic rhinosinusitis allergic fungal rhinosinusitis Medicine (General) R5-920
spellingShingle	vitamin d3, sino-nasal polypi, chronic rhinosinusitis allergic fungal rhinosinusitis Medicine (General) R5-920 Ali Abdel-Rahman Mahmoud El-Sobky Amr Rezk Mohamed Emara Evaluation of Vitamin D3 level in Sino-nasal Polypi
description	Background: Vitamin D is a group of fat-soluble corticosteroid responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects. In humans, the most important compounds in this group are vitamin D3 [also known as cholecalciferol] and vitamin D2 [ergocalciferol].Aim of the work: The aim of this thesis is to assess Vitamin D3 [VD3] level in patients with sino-nasal polypi in comparison with normal individuals.Patients and Methods: This prospective comparative [case-control] study conducted by the Department of ENT, Al-Azhar University Hospitals in the period from March 2019 to September 2019 and included 40 individuals who were selected by inclusion and exclusion criteria, both genders, all patients had been counseled about the nature of the study and informed written consent has been obtained.Results: Serum level of VD3 in patients with chronic rhinosinusitis with sinonasal polyps [CRSwNP] and allergic fungal rhinosinusitis [AFRS] was significantly lower than that of control subjects. Vitamin D levels ranged from 8.74 to 39 ng/ml, and there was statistically significant decrease of serum vitamin D levels in patient group when compared to control group [16.20±4.29 vs 30.56±4.83 respectively]. In addition, there was significant increase of patients with deficient and insufficient vitamin D levels in patient group when compared to control group.Conclusion: VD3 may constitute an inexpensive prophylactic and cost effective option in the therapeutic armamentarium in reducing inflammation either by itself or as a synergistic agent to traditional agents in patients suffering from sino-nasal polypi.
format	article
author	Ali Abdel-Rahman Mahmoud El-Sobky Amr Rezk Mohamed Emara
author_facet	Ali Abdel-Rahman Mahmoud El-Sobky Amr Rezk Mohamed Emara
author_sort	Ali Abdel-Rahman
title	Evaluation of Vitamin D3 level in Sino-nasal Polypi
title_short	Evaluation of Vitamin D3 level in Sino-nasal Polypi
title_full	Evaluation of Vitamin D3 level in Sino-nasal Polypi
title_fullStr	Evaluation of Vitamin D3 level in Sino-nasal Polypi
title_full_unstemmed	Evaluation of Vitamin D3 level in Sino-nasal Polypi
title_sort	evaluation of vitamin d3 level in sino-nasal polypi
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2019
url	https://doaj.org/article/3651455b833d41e8a3d330fd0e9cb036
work_keys_str_mv	AT aliabdelrahman evaluationofvitamind3levelinsinonasalpolypi AT mahmoudelsobky evaluationofvitamind3levelinsinonasalpolypi AT amrrezk evaluationofvitamind3levelinsinonasalpolypi AT mohamedemara evaluationofvitamind3levelinsinonasalpolypi
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Evaluation of Vitamin D3 level in Sino-nasal Polypi

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