The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment
While Spinal Cord Stimulation (SCS) provides satisfaction to almost 2/3 of Persistent Spinal Pain Syndrome-Type 2 (PSPS-T2) patients implanted for refractory chronic back and/or leg pain, when not adequately addressed the back pain component, leaves patients in a therapeutic cul-de-sac. Peripheral N...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/365c6b2f4bb048198af7aa41a3e499dc |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:365c6b2f4bb048198af7aa41a3e499dc |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:365c6b2f4bb048198af7aa41a3e499dc2021-11-11T17:42:58ZThe Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment10.3390/jcm102150942077-0383https://doaj.org/article/365c6b2f4bb048198af7aa41a3e499dc2021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5094https://doaj.org/toc/2077-0383While Spinal Cord Stimulation (SCS) provides satisfaction to almost 2/3 of Persistent Spinal Pain Syndrome-Type 2 (PSPS-T2) patients implanted for refractory chronic back and/or leg pain, when not adequately addressed the back pain component, leaves patients in a therapeutic cul-de-sac. Peripheral Nerve field Stimulation (PNfS) has shown interesting results addressing back pain in the same population. Far from placing these two techniques in opposition, we suggest that these approaches could be combined to better treat PSPS-T2 patients. We designed a RCT (CUMPNS), with a 12-month follow-up, to assess the potential added value of PNfS, as a salvage therapy, in PSPS-T2 patients experiencing a “Failed SCS Syndrome” in the back pain component. Fourteen patients were included in this study and randomized into 2 groups (“SCS + PNfS” group/<i>n</i> = 6 vs. “SCS only” group/<i>n</i> = 8). The primary objective of the study was to compare the percentage of back pain surface decrease after 3 months, using a computerized interface to obtain quantitative pain mappings, combined with multi-dimensional SCS outcomes. Back pain surface decreased significantly greater for the ”SCS + PNfS” group (80.2% ± 21.3%) compared to the “SCS only” group (13.2% ± 94.8%) (<i>p</i> = 0.012), highlighting the clinical interest of SCS + PNfS, in cases where SCS fails to address back pain.Philippe RigoardAmine OunajimLisa GoudmanBenedicte BoucheManuel RoulaudPhilippe PageBertille LorgeouxSandrine BaronKevin NivoleMathilde ManyNihel AdjaliElodie CharrierDelphine RannouLaure PoupinChantal WoodRomain DavidDylan HéraudMaartens MoensMaxime BillotMDPI AGarticleSpinal Cord StimulationSubQ-stimulationHybrid StimulationMultidimensional Pain assessmentPain MappingFailed Back Surgery Syndrome (FBSS)MedicineRENJournal of Clinical Medicine, Vol 10, Iss 5094, p 5094 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Spinal Cord Stimulation SubQ-stimulation Hybrid Stimulation Multidimensional Pain assessment Pain Mapping Failed Back Surgery Syndrome (FBSS) Medicine R |
| spellingShingle |
Spinal Cord Stimulation SubQ-stimulation Hybrid Stimulation Multidimensional Pain assessment Pain Mapping Failed Back Surgery Syndrome (FBSS) Medicine R Philippe Rigoard Amine Ounajim Lisa Goudman Benedicte Bouche Manuel Roulaud Philippe Page Bertille Lorgeoux Sandrine Baron Kevin Nivole Mathilde Many Nihel Adjali Elodie Charrier Delphine Rannou Laure Poupin Chantal Wood Romain David Dylan Héraud Maartens Moens Maxime Billot The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| description |
While Spinal Cord Stimulation (SCS) provides satisfaction to almost 2/3 of Persistent Spinal Pain Syndrome-Type 2 (PSPS-T2) patients implanted for refractory chronic back and/or leg pain, when not adequately addressed the back pain component, leaves patients in a therapeutic cul-de-sac. Peripheral Nerve field Stimulation (PNfS) has shown interesting results addressing back pain in the same population. Far from placing these two techniques in opposition, we suggest that these approaches could be combined to better treat PSPS-T2 patients. We designed a RCT (CUMPNS), with a 12-month follow-up, to assess the potential added value of PNfS, as a salvage therapy, in PSPS-T2 patients experiencing a “Failed SCS Syndrome” in the back pain component. Fourteen patients were included in this study and randomized into 2 groups (“SCS + PNfS” group/<i>n</i> = 6 vs. “SCS only” group/<i>n</i> = 8). The primary objective of the study was to compare the percentage of back pain surface decrease after 3 months, using a computerized interface to obtain quantitative pain mappings, combined with multi-dimensional SCS outcomes. Back pain surface decreased significantly greater for the ”SCS + PNfS” group (80.2% ± 21.3%) compared to the “SCS only” group (13.2% ± 94.8%) (<i>p</i> = 0.012), highlighting the clinical interest of SCS + PNfS, in cases where SCS fails to address back pain. |
| format |
article |
| author |
Philippe Rigoard Amine Ounajim Lisa Goudman Benedicte Bouche Manuel Roulaud Philippe Page Bertille Lorgeoux Sandrine Baron Kevin Nivole Mathilde Many Nihel Adjali Elodie Charrier Delphine Rannou Laure Poupin Chantal Wood Romain David Dylan Héraud Maartens Moens Maxime Billot |
| author_facet |
Philippe Rigoard Amine Ounajim Lisa Goudman Benedicte Bouche Manuel Roulaud Philippe Page Bertille Lorgeoux Sandrine Baron Kevin Nivole Mathilde Many Nihel Adjali Elodie Charrier Delphine Rannou Laure Poupin Chantal Wood Romain David Dylan Héraud Maartens Moens Maxime Billot |
| author_sort |
Philippe Rigoard |
| title |
The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| title_short |
The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| title_full |
The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| title_fullStr |
The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| title_full_unstemmed |
The Added Value of Subcutaneous Peripheral Nerve Field Stimulation Combined with SCS, as Salvage Therapy, for Refractory Low Back Pain Component in Persistent Spinal Pain Syndrome Implanted Patients: A Randomized Controlled Study (CUMPNS Study) Based on 3D-Mapping Composite Pain Assessment |
| title_sort |
added value of subcutaneous peripheral nerve field stimulation combined with scs, as salvage therapy, for refractory low back pain component in persistent spinal pain syndrome implanted patients: a randomized controlled study (cumpns study) based on 3d-mapping composite pain assessment |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/365c6b2f4bb048198af7aa41a3e499dc |
| work_keys_str_mv |
AT philipperigoard theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT amineounajim theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT lisagoudman theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT benedictebouche theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT manuelroulaud theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT philippepage theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT bertillelorgeoux theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT sandrinebaron theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT kevinnivole theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT mathildemany theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT niheladjali theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT elodiecharrier theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT delphinerannou theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT laurepoupin theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT chantalwood theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT romaindavid theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT dylanheraud theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT maartensmoens theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT maximebillot theaddedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT philipperigoard addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT amineounajim addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT lisagoudman addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT benedictebouche addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT manuelroulaud addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT philippepage addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT bertillelorgeoux addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT sandrinebaron addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT kevinnivole addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT mathildemany addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT niheladjali addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT elodiecharrier addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT delphinerannou addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT laurepoupin addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT chantalwood addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT romaindavid addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT dylanheraud addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT maartensmoens addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment AT maximebillot addedvalueofsubcutaneousperipheralnervefieldstimulationcombinedwithscsassalvagetherapyforrefractorylowbackpaincomponentinpersistentspinalpainsyndromeimplantedpatientsarandomizedcontrolledstudycumpnsstudybasedon3dmappingcompositepainassessment |
| _version_ |
1718431995044823040 |