Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

Targeted therapies for solid tumors in children, adolescents, and young adults (C-AYA) lag behind that of adult carcinomas. Here, the authors study the germline genomic signatures of 1,507 C-AYA patients with solid tumors and find pathogenic/likely pathogenic germline variants in diverse genes of wh...

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Autores principales: Sara Akhavanfard, Roshan Padmanabhan, Lamis Yehia, Feixiong Cheng, Charis Eng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/36633244b1ef47a0af16dac7729a6ae5
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