Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

Targeted therapies for solid tumors in children, adolescents, and young adults (C-AYA) lag behind that of adult carcinomas. Here, the authors study the germline genomic signatures of 1,507 C-AYA patients with solid tumors and find pathogenic/likely pathogenic germline variants in diverse genes of wh...

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Bibliographic Details
Main Authors: Sara Akhavanfard, Roshan Padmanabhan, Lamis Yehia, Feixiong Cheng, Charis Eng
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/36633244b1ef47a0af16dac7729a6ae5
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