A report of radiographic manifestations of 32 patients with Histiocytosis X

Objective: Histiocytosis-X (H-X) is more common in children who are under 12 years. It involves different organs such as bone, lung, liver, spleen and skin. The purpose of this study was to investigate about radiographic findings of patients with H-X that have been confirmed by pathology. Methods: T...

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Autores principales: N Ghojeh Vand, M Nabahati
Formato: article
Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2001
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Acceso en línea:https://doaj.org/article/366979fb8416453babfcc18b726b2ad3
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spelling oai:doaj.org-article:366979fb8416453babfcc18b726b2ad32021-11-10T09:21:07ZA report of radiographic manifestations of 32 patients with Histiocytosis X1561-41072251-7170https://doaj.org/article/366979fb8416453babfcc18b726b2ad32001-07-01T00:00:00Zhttp://jbums.org/article-1-2867-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Histiocytosis-X (H-X) is more common in children who are under 12 years. It involves different organs such as bone, lung, liver, spleen and skin. The purpose of this study was to investigate about radiographic findings of patients with H-X that have been confirmed by pathology. Methods: This descriptive study was done to survey radiographic findings on patients with H-X. We studied the files and graphs of 32 cases who were hospitalized in Mofid hospital (Tehran) during 1980-2000 with a confirmed pathological diagnosis after taking biopsy from different tissues such as skin, lymph node and bone. Findings: From 32 patients, 29 cases had bone involvement with involvement of flat bones more common than long bones in which metaphyses of long bones were more commonly involved than diaphyses. Lytic lesion with a defined limit and without sclerotic margins was the most common radiologic finding. In 23 cases, among the flat bones, skull was the most commonly involved bone. Vertebral involvement as vertebra plana and bilateral destruction of mastoid were observed in 5 and 3 patients respectively. In 12 patients, pulmonary involvement was noted with reticulonodular involvement as the most common radiologic findings. Conclusion: In this disease, the bones especially flat bones were the most commonly involved. In long bones, the involvement of metaphysis was more than diaphysis.N Ghojeh VandM NabahatiBabol University of Medical Sciencesarticlehistiocytosis-xboneslytic lesionsMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 3, Iss 3, Pp 59-63 (2001)
institution DOAJ
collection DOAJ
language EN
FA
topic histiocytosis-x
bones
lytic lesions
Medicine
R
Medicine (General)
R5-920
spellingShingle histiocytosis-x
bones
lytic lesions
Medicine
R
Medicine (General)
R5-920
N Ghojeh Vand
M Nabahati
A report of radiographic manifestations of 32 patients with Histiocytosis X
description Objective: Histiocytosis-X (H-X) is more common in children who are under 12 years. It involves different organs such as bone, lung, liver, spleen and skin. The purpose of this study was to investigate about radiographic findings of patients with H-X that have been confirmed by pathology. Methods: This descriptive study was done to survey radiographic findings on patients with H-X. We studied the files and graphs of 32 cases who were hospitalized in Mofid hospital (Tehran) during 1980-2000 with a confirmed pathological diagnosis after taking biopsy from different tissues such as skin, lymph node and bone. Findings: From 32 patients, 29 cases had bone involvement with involvement of flat bones more common than long bones in which metaphyses of long bones were more commonly involved than diaphyses. Lytic lesion with a defined limit and without sclerotic margins was the most common radiologic finding. In 23 cases, among the flat bones, skull was the most commonly involved bone. Vertebral involvement as vertebra plana and bilateral destruction of mastoid were observed in 5 and 3 patients respectively. In 12 patients, pulmonary involvement was noted with reticulonodular involvement as the most common radiologic findings. Conclusion: In this disease, the bones especially flat bones were the most commonly involved. In long bones, the involvement of metaphysis was more than diaphysis.
format article
author N Ghojeh Vand
M Nabahati
author_facet N Ghojeh Vand
M Nabahati
author_sort N Ghojeh Vand
title A report of radiographic manifestations of 32 patients with Histiocytosis X
title_short A report of radiographic manifestations of 32 patients with Histiocytosis X
title_full A report of radiographic manifestations of 32 patients with Histiocytosis X
title_fullStr A report of radiographic manifestations of 32 patients with Histiocytosis X
title_full_unstemmed A report of radiographic manifestations of 32 patients with Histiocytosis X
title_sort report of radiographic manifestations of 32 patients with histiocytosis x
publisher Babol University of Medical Sciences
publishDate 2001
url https://doaj.org/article/366979fb8416453babfcc18b726b2ad3
work_keys_str_mv AT nghojehvand areportofradiographicmanifestationsof32patientswithhistiocytosisx
AT mnabahati areportofradiographicmanifestationsof32patientswithhistiocytosisx
AT nghojehvand reportofradiographicmanifestationsof32patientswithhistiocytosisx
AT mnabahati reportofradiographicmanifestationsof32patientswithhistiocytosisx
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