Sacubitril-Valsartan, Clinical Benefits and Related Mechanisms of Action in Heart Failure With Reduced Ejection Fraction. A Review

Heart failure (HF) is a clinical syndrome characterized by the presence of dyspnea or limited exertion due to impaired cardiac ventricular filling and/or blood ejection. Because of its high prevalence, it is a major health and economic burden worldwide. Several mechanisms are involved in the pathoph...

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Main Authors: Domingo Pascual-Figal, Antoni Bayés-Genis, Paola Beltrán-Troncoso, Pedro Caravaca-Pérez, Alicia Conde-Martel, Maria G. Crespo-Leiro, Juan F. Delgado, Javier Díez, Francesc Formiga, Nicolás Manito
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/367a0118f2f647ed9ac35f91293314da
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