Tadalafil Modulates Intracerebroventricular Streptozotocin-Induced Cognition and Memory Impairment in the Young and Middle-Aged Rats

Background: Learning and memory may decline due to Alzheimer’s disease (AD) in older adults. A reduction in cyclic guanosine monophosphate concentration and an increase in phosphodiesterase activity have been reported in the process of aging. Althoughphosphodiesterase (PDE) type 5 inhibitor, Tadalaf...

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Bibliographic Details
Main Authors: Siamak Shahidi, Masoumeh Asadbegi, Nasrin Hashemi-Firouzi, Alireza Komaki, Minoo Mahmoodi
Format: article
Language:EN
Published: Tabriz University of Medical Sciences 2021
Subjects:
rat
Online Access:https://doaj.org/article/367a07e32fb547a58191f8f2152b75f7
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