Epstein–Barr virus particles induce centrosome amplification and chromosomal instability

Infection with Epstein–Barr virus (EBV) is associated with increased risk of cancer development. Here the authors show that EBV particles, and more specifically the viral protein BNRF1, induce centrosome amplification and chromosomal instability in host cells in the absence of chronic infection.

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Autores principales:	Anatoliy Shumilov, Ming-Han Tsai, Yvonne T. Schlosser, Anne-Sophie Kratz, Katharina Bernhardt, Susanne Fink, Tuba Mizani, Xiaochen Lin, Anna Jauch, Josef Mautner, Annette Kopp-Schneider, Regina Feederle, Ingrid Hoffmann, Henri-Jacques Delecluse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3689664b91e643c698c471add004eaab
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spelling	oai:doaj.org-article:3689664b91e643c698c471add004eaab2021-12-02T14:42:39ZEpstein–Barr virus particles induce centrosome amplification and chromosomal instability10.1038/ncomms142572041-1723https://doaj.org/article/3689664b91e643c698c471add004eaab2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14257https://doaj.org/toc/2041-1723Infection with Epstein–Barr virus (EBV) is associated with increased risk of cancer development. Here the authors show that EBV particles, and more specifically the viral protein BNRF1, induce centrosome amplification and chromosomal instability in host cells in the absence of chronic infection.Anatoliy ShumilovMing-Han TsaiYvonne T. SchlosserAnne-Sophie KratzKatharina BernhardtSusanne FinkTuba MizaniXiaochen LinAnna JauchJosef MautnerAnnette Kopp-SchneiderRegina FeederleIngrid HoffmannHenri-Jacques DelecluseNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anatoliy Shumilov Ming-Han Tsai Yvonne T. Schlosser Anne-Sophie Kratz Katharina Bernhardt Susanne Fink Tuba Mizani Xiaochen Lin Anna Jauch Josef Mautner Annette Kopp-Schneider Regina Feederle Ingrid Hoffmann Henri-Jacques Delecluse Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
description	Infection with Epstein–Barr virus (EBV) is associated with increased risk of cancer development. Here the authors show that EBV particles, and more specifically the viral protein BNRF1, induce centrosome amplification and chromosomal instability in host cells in the absence of chronic infection.
format	article
author	Anatoliy Shumilov Ming-Han Tsai Yvonne T. Schlosser Anne-Sophie Kratz Katharina Bernhardt Susanne Fink Tuba Mizani Xiaochen Lin Anna Jauch Josef Mautner Annette Kopp-Schneider Regina Feederle Ingrid Hoffmann Henri-Jacques Delecluse
author_facet	Anatoliy Shumilov Ming-Han Tsai Yvonne T. Schlosser Anne-Sophie Kratz Katharina Bernhardt Susanne Fink Tuba Mizani Xiaochen Lin Anna Jauch Josef Mautner Annette Kopp-Schneider Regina Feederle Ingrid Hoffmann Henri-Jacques Delecluse
author_sort	Anatoliy Shumilov
title	Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
title_short	Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
title_full	Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
title_fullStr	Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
title_full_unstemmed	Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
title_sort	epstein–barr virus particles induce centrosome amplification and chromosomal instability
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3689664b91e643c698c471add004eaab
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Epstein–Barr virus particles induce centrosome amplification and chromosomal instability

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