Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)

The increase in total cholesterol level increases the risk of cardiovascular disease. Sweet potato leaves are a food that contains polyphenols, flavonoids, quercetin, tannin, and fiber that effectively lower total cholesterol levels. This study aims to analyze the effect of ethanol extracts of leaf...

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Autores principales:	Siti Fatimah, Desto Arisandi, Meirina Sindi Saputri
Formato:	article
Lenguaje:	ID
Publicado:	LPPM STIKES Guna Bangsa Yogyakarta 2018
Materias:	total cholesterol extracts leaf purple sweet potato Medicine R
Acceso en línea:	https://doaj.org/article/369a152b635449de93660a1de725346e
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spelling	oai:doaj.org-article:369a152b635449de93660a1de725346e2021-11-12T14:08:32ZTotal Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)2355-88572407-637610.30590/vol5-no1-p33-39https://doaj.org/article/369a152b635449de93660a1de725346e2018-01-01T00:00:00Zhttps://journal.gunabangsa.ac.id/index.php/joh/article/view/118https://doaj.org/toc/2355-8857https://doaj.org/toc/2407-6376The increase in total cholesterol level increases the risk of cardiovascular disease. Sweet potato leaves are a food that contains polyphenols, flavonoids, quercetin, tannin, and fiber that effectively lower total cholesterol levels. This study aims to analyze the effect of ethanol extracts of leaf purple sweet potato on serum total cholesterol levels of rats fed a high-fat diet. An experimental study with design pre and posttest carried out on 10 male Wistar rats (Rattus norvegicus) fed a high-fat, which are 2 groups: 1 group the control hypercholesterolemia and 1 group ethanol extracts of leaf purple sweet potato. Dose based on leaves of quercetin that is equal to 2 mg/kgBB. The average content of quercetin ethanol extracts of leaf purple sweet potato was analyzed to obtain 14,08 mg/100g. Ethanol extracts of leaf purple sweet potato are given for 14 days by way of on the sonde. Serum total cholesterol was determined by the CHOD-PAP method. The data obtained were analyzed descriptively.The result of this study obtained the average total cholesterol level of white blood rats before giving ethanol extracts of leaf purple sweet potato that is 189,89 mg/dl, whereas after administration of ethanol extracts of leaf purple sweet potato dose 2 mg/kgBB that is 131,92 mg/dl. The decrease in total cholesterol level of white rats after giving ethanol extracts of leaf purple sweet potato with dose 2 mg/kgBB that is 30,52 %.Siti FatimahDesto ArisandiMeirina Sindi SaputriLPPM STIKES Guna Bangsa Yogyakartaarticletotal cholesterolextractsleaf purple sweet potatoMedicineRIDJournal of Health (JOH), Vol 5, Iss 1, Pp 33-39 (2018)
institution	DOAJ
collection	DOAJ
language	ID
topic	total cholesterol extracts leaf purple sweet potato Medicine R
spellingShingle	total cholesterol extracts leaf purple sweet potato Medicine R Siti Fatimah Desto Arisandi Meirina Sindi Saputri Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
description	The increase in total cholesterol level increases the risk of cardiovascular disease. Sweet potato leaves are a food that contains polyphenols, flavonoids, quercetin, tannin, and fiber that effectively lower total cholesterol levels. This study aims to analyze the effect of ethanol extracts of leaf purple sweet potato on serum total cholesterol levels of rats fed a high-fat diet. An experimental study with design pre and posttest carried out on 10 male Wistar rats (Rattus norvegicus) fed a high-fat, which are 2 groups: 1 group the control hypercholesterolemia and 1 group ethanol extracts of leaf purple sweet potato. Dose based on leaves of quercetin that is equal to 2 mg/kgBB. The average content of quercetin ethanol extracts of leaf purple sweet potato was analyzed to obtain 14,08 mg/100g. Ethanol extracts of leaf purple sweet potato are given for 14 days by way of on the sonde. Serum total cholesterol was determined by the CHOD-PAP method. The data obtained were analyzed descriptively.The result of this study obtained the average total cholesterol level of white blood rats before giving ethanol extracts of leaf purple sweet potato that is 189,89 mg/dl, whereas after administration of ethanol extracts of leaf purple sweet potato dose 2 mg/kgBB that is 131,92 mg/dl. The decrease in total cholesterol level of white rats after giving ethanol extracts of leaf purple sweet potato with dose 2 mg/kgBB that is 30,52 %.
format	article
author	Siti Fatimah Desto Arisandi Meirina Sindi Saputri
author_facet	Siti Fatimah Desto Arisandi Meirina Sindi Saputri
author_sort	Siti Fatimah
title	Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
title_short	Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
title_full	Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
title_fullStr	Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
title_full_unstemmed	Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)
title_sort	total cholesterol level of hypercholesterolemia male wistar rats (rattus norvegicus) with ethanol extracts of purple sweet potato leaf (ipomoea batatas (l.) lam)
publisher	LPPM STIKES Guna Bangsa Yogyakarta
publishDate	2018
url	https://doaj.org/article/369a152b635449de93660a1de725346e
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Total Cholesterol Level of Hypercholesterolemia Male Wistar Rats (Rattus norvegicus) with Ethanol Extracts of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Lam)

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