DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

Altered epigenetics is a feature of cancer but whether these changes occur early in tumour development is unclear. Here, the authors analyse methylation events in breast cancer and adjacent normal pairs, and show that methylation changes in the normal tissue are also found in the tumour, suggesting...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrew E Teschendorff, Yang Gao, Allison Jones, Matthias Ruebner, Matthias W. Beckmann, David L. Wachter, Peter A. Fasching, Martin Widschwendter
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/36a2ba29445c4d0cb50f78cab96cf024
Tags: Add Tag
No Tags, Be the first to tag this record!