A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer

Congo Tak-Shing Ching1,2, Tai-Ping Sun1,2, Su-Hua Huang3, Chin-Sung Hsiao4, Ching-Haur Chang4, Shiow-Yuan Huang4, Yi-Juai Chen5, Chi-Sheng Cheng6, Hsiu-Li Shieh2, Chung-Yuan Chen21Graduate Institute of Biomedicine and Biomedical Technology, National Chi Nan University, Nantou, Taiwan; 2Department of...

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Autores principales:	Congo Tak-Shing Ching, Tai-Ping Sun, Su-Hua Huang, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/36a93ecf5e704026a625d5e1f696cee7
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spelling	oai:doaj.org-article:36a93ecf5e704026a625d5e1f696cee72021-12-02T02:57:20ZA preliminary study of the use of bioimpedance in the screening of squamous tongue cancer1176-91141178-2013https://doaj.org/article/36a93ecf5e704026a625d5e1f696cee72010-03-01T00:00:00Zhttp://www.dovepress.com/a-preliminary-study-of-the-use-of-bioimpedance-in-the-screening-of-squ-a4103https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Congo Tak-Shing Ching1,2, Tai-Ping Sun1,2, Su-Hua Huang3, Chin-Sung Hsiao4, Ching-Haur Chang4, Shiow-Yuan Huang4, Yi-Juai Chen5, Chi-Sheng Cheng6, Hsiu-Li Shieh2, Chung-Yuan Chen21Graduate Institute of Biomedicine and Biomedical Technology, National Chi Nan University, Nantou, Taiwan; 2Department of Electrical Engineering, National Chi Nan University, Nantou, Taiwan; 3Department of&nbsp; Biotechnology, Asia University, Taichung, Taiwan; 4Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan; 5Department of Oral and Maxillofacial Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan; 6Department of Oral and Maxillofacial Surgery, Taichung Veterans General Hospital, Taichung, TaiwanAbstract: Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue tissue (NTT). Five tongue cancer patients participated in this study. A disposable probe incorporating four silver electrodes was used to measure the electrical properties of CTT and the surrounding NTT of patients. Measurements were performed at six frequencies: 20 Hz; 50 kHz; 1.3 MHz; 2.5 MHz; 3.7 MHz; and 5 MHz, with the amplitude of the applied voltage limited to 200mV. Four measurement parameters of impedance (Z), phase angle (&theta;), real part of impedance (R), and imaginary part of impedance (X) of tongue tissue were assessed to see if there was any significant difference in the values obtained in CTT and surrounding NTT. The intraclass correlation coefficient showed that all measurements were reliable. A significant difference (P &lt; 0.05 for the four measurement parameters) was found at 50kHz between CTT and surrounding NTT. It was also found that Z and R of CTT were generally smaller than that of surrounding NTT. In conclusion, bioimpedance at a particular frequency is a potentially promising technique for tongue cancer screening.Keywords: bioimpedance, tongue, cancer, noninvasive, detection, screening Congo Tak-Shing ChingTai-Ping SunSu-Hua Huanget alDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2010, Iss default, Pp 213-220 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Congo Tak-Shing Ching Tai-Ping Sun Su-Hua Huang et al A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
description	Congo Tak-Shing Ching1,2, Tai-Ping Sun1,2, Su-Hua Huang3, Chin-Sung Hsiao4, Ching-Haur Chang4, Shiow-Yuan Huang4, Yi-Juai Chen5, Chi-Sheng Cheng6, Hsiu-Li Shieh2, Chung-Yuan Chen21Graduate Institute of Biomedicine and Biomedical Technology, National Chi Nan University, Nantou, Taiwan; 2Department of Electrical Engineering, National Chi Nan University, Nantou, Taiwan; 3Department of&nbsp; Biotechnology, Asia University, Taichung, Taiwan; 4Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan; 5Department of Oral and Maxillofacial Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan; 6Department of Oral and Maxillofacial Surgery, Taichung Veterans General Hospital, Taichung, TaiwanAbstract: Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue tissue (NTT). Five tongue cancer patients participated in this study. A disposable probe incorporating four silver electrodes was used to measure the electrical properties of CTT and the surrounding NTT of patients. Measurements were performed at six frequencies: 20 Hz; 50 kHz; 1.3 MHz; 2.5 MHz; 3.7 MHz; and 5 MHz, with the amplitude of the applied voltage limited to 200mV. Four measurement parameters of impedance (Z), phase angle (&theta;), real part of impedance (R), and imaginary part of impedance (X) of tongue tissue were assessed to see if there was any significant difference in the values obtained in CTT and surrounding NTT. The intraclass correlation coefficient showed that all measurements were reliable. A significant difference (P &lt; 0.05 for the four measurement parameters) was found at 50kHz between CTT and surrounding NTT. It was also found that Z and R of CTT were generally smaller than that of surrounding NTT. In conclusion, bioimpedance at a particular frequency is a potentially promising technique for tongue cancer screening.Keywords: bioimpedance, tongue, cancer, noninvasive, detection, screening
format	article
author	Congo Tak-Shing Ching Tai-Ping Sun Su-Hua Huang et al
author_facet	Congo Tak-Shing Ching Tai-Ping Sun Su-Hua Huang et al
author_sort	Congo Tak-Shing Ching
title	A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_short	A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_full	A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_fullStr	A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_full_unstemmed	A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_sort	preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/36a93ecf5e704026a625d5e1f696cee7
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A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer

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