Diagnosis, prevention, and management of canine hip dysplasia: a review

Emma R Schachner, Mandi J Lopez Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA Abstract: Canine hip dysplasia (CHD) is a polygenic and multifactorial developmental disorder characterized by coxofemoral (hip) joint laxity,...

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Autores principales:	Schachner ER, Lopez MJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/36acde8a240a4ed79299fe510398cf9e
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spelling	oai:doaj.org-article:36acde8a240a4ed79299fe510398cf9e2021-12-02T00:09:32ZDiagnosis, prevention, and management of canine hip dysplasia: a review2230-2034https://doaj.org/article/36acde8a240a4ed79299fe510398cf9e2015-05-01T00:00:00Zhttp://www.dovepress.com/diagnosis-prevention-and-management-of-canine-hip-dysplasia-a-review-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034Emma R Schachner, Mandi J Lopez Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA Abstract: Canine hip dysplasia (CHD) is a polygenic and multifactorial developmental disorder characterized by coxofemoral (hip) joint laxity, degeneration, and osteoarthritis (OA). Current diagnostic techniques are largely subjective measures of joint conformation performed at different stages of development. Recently, measures on three-dimensional images generated from computed tomography scans predicted the development of OA associated with CHD. Continued refinement of similar imaging methods may improve diagnostic imaging techniques to identify dogs predisposed to degenerative hip joint changes. By current consensus, joint changes consistent with CHD are influenced by genetic predisposition as well as environmental and biomechanical factors; however, despite decades of work, the relative contributions of each to the development and extent of CHD signs remain elusive. Similarly, despite considerable effort to decipher the genetic underpinnings of CHD for selective breeding programs, relevant genetic loci remain equivocal. As such, prevention of CHD within domestic canine populations is marginally successful. Conservative management is often employed to manage signs of CHD, with lifelong maintenance of body mass as one of the most promising methods. Surgical intervention is often employed to prevent joint changes or restore joint function, but there are no gold standards for either goal. To date, all CHD phenotypes are considered as a single entity in spite of recognized differences in expression and response to environmental conditions and treatment. Identification of distinct CHD phenotypes and targeting evidence-based conservative and invasive treatments for each may significantly advance prevention and management of a prevalent, debilitating condition in canine companions. Keywords: canine hip dysplasia, orthopedics, joint, osteoarthritisSchachner ERLopez MJDove Medical PressarticleVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol 2015, Iss default, Pp 181-192 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Veterinary medicine SF600-1100
spellingShingle	Veterinary medicine SF600-1100 Schachner ER Lopez MJ Diagnosis, prevention, and management of canine hip dysplasia: a review
description	Emma R Schachner, Mandi J Lopez Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA Abstract: Canine hip dysplasia (CHD) is a polygenic and multifactorial developmental disorder characterized by coxofemoral (hip) joint laxity, degeneration, and osteoarthritis (OA). Current diagnostic techniques are largely subjective measures of joint conformation performed at different stages of development. Recently, measures on three-dimensional images generated from computed tomography scans predicted the development of OA associated with CHD. Continued refinement of similar imaging methods may improve diagnostic imaging techniques to identify dogs predisposed to degenerative hip joint changes. By current consensus, joint changes consistent with CHD are influenced by genetic predisposition as well as environmental and biomechanical factors; however, despite decades of work, the relative contributions of each to the development and extent of CHD signs remain elusive. Similarly, despite considerable effort to decipher the genetic underpinnings of CHD for selective breeding programs, relevant genetic loci remain equivocal. As such, prevention of CHD within domestic canine populations is marginally successful. Conservative management is often employed to manage signs of CHD, with lifelong maintenance of body mass as one of the most promising methods. Surgical intervention is often employed to prevent joint changes or restore joint function, but there are no gold standards for either goal. To date, all CHD phenotypes are considered as a single entity in spite of recognized differences in expression and response to environmental conditions and treatment. Identification of distinct CHD phenotypes and targeting evidence-based conservative and invasive treatments for each may significantly advance prevention and management of a prevalent, debilitating condition in canine companions. Keywords: canine hip dysplasia, orthopedics, joint, osteoarthritis
format	article
author	Schachner ER Lopez MJ
author_facet	Schachner ER Lopez MJ
author_sort	Schachner ER
title	Diagnosis, prevention, and management of canine hip dysplasia: a review
title_short	Diagnosis, prevention, and management of canine hip dysplasia: a review
title_full	Diagnosis, prevention, and management of canine hip dysplasia: a review
title_fullStr	Diagnosis, prevention, and management of canine hip dysplasia: a review
title_full_unstemmed	Diagnosis, prevention, and management of canine hip dysplasia: a review
title_sort	diagnosis, prevention, and management of canine hip dysplasia: a review
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/36acde8a240a4ed79299fe510398cf9e
work_keys_str_mv	AT schachnerer diagnosispreventionandmanagementofcaninehipdysplasiaareview AT lopezmj diagnosispreventionandmanagementofcaninehipdysplasiaareview
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Diagnosis, prevention, and management of canine hip dysplasia: a review

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