NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice

Gunn Hildrestrand, Veslemøy Rolseth, and Nicolas Kunath et al. examine mice lacking the NEIL1 and NEIL2 DNA glycosylases involved in base excision repair. Their results suggest that loss of both NEIL1 and NEIL2 dysregulates genes relevant to synaptic function and modulates behavior in mice.

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Autores principales:	Gunn A. Hildrestrand, Veslemøy Rolseth, Nicolas Kunath, Rajikala Suganthan, Vidar Jensen, Anna M. Bugaj, Marion S. Fernandez-Berrocal, Sunniva B. Sikko, Susanne Vetlesen, Anna Kuśnierczyk, Ann-Karin Olsen, Kristine B. Gützkow, Alexander D. Rowe, Wei Wang, Olve Moldestad, Monica D. Syrstad, Geir Slupphaug, Lars Eide, Arne Klungland, Pål Sætrom, Luisa Luna, Jing Ye, Katja Scheffler, Magnar Bjørås
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/36b704fa17dc44b1933173201d933187
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spelling	oai:doaj.org-article:36b704fa17dc44b1933173201d9331872021-12-05T12:08:07ZNEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice10.1038/s42003-021-02864-x2399-3642https://doaj.org/article/36b704fa17dc44b1933173201d9331872021-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02864-xhttps://doaj.org/toc/2399-3642Gunn Hildrestrand, Veslemøy Rolseth, and Nicolas Kunath et al. examine mice lacking the NEIL1 and NEIL2 DNA glycosylases involved in base excision repair. Their results suggest that loss of both NEIL1 and NEIL2 dysregulates genes relevant to synaptic function and modulates behavior in mice.Gunn A. HildrestrandVeslemøy RolsethNicolas KunathRajikala SuganthanVidar JensenAnna M. BugajMarion S. Fernandez-BerrocalSunniva B. SikkoSusanne VetlesenAnna KuśnierczykAnn-Karin OlsenKristine B. GützkowAlexander D. RoweWei WangOlve MoldestadMonica D. SyrstadGeir SlupphaugLars EideArne KlunglandPål SætromLuisa LunaJing YeKatja SchefflerMagnar BjøråsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Gunn A. Hildrestrand Veslemøy Rolseth Nicolas Kunath Rajikala Suganthan Vidar Jensen Anna M. Bugaj Marion S. Fernandez-Berrocal Sunniva B. Sikko Susanne Vetlesen Anna Kuśnierczyk Ann-Karin Olsen Kristine B. Gützkow Alexander D. Rowe Wei Wang Olve Moldestad Monica D. Syrstad Geir Slupphaug Lars Eide Arne Klungland Pål Sætrom Luisa Luna Jing Ye Katja Scheffler Magnar Bjørås NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
description	Gunn Hildrestrand, Veslemøy Rolseth, and Nicolas Kunath et al. examine mice lacking the NEIL1 and NEIL2 DNA glycosylases involved in base excision repair. Their results suggest that loss of both NEIL1 and NEIL2 dysregulates genes relevant to synaptic function and modulates behavior in mice.
format	article
author	Gunn A. Hildrestrand Veslemøy Rolseth Nicolas Kunath Rajikala Suganthan Vidar Jensen Anna M. Bugaj Marion S. Fernandez-Berrocal Sunniva B. Sikko Susanne Vetlesen Anna Kuśnierczyk Ann-Karin Olsen Kristine B. Gützkow Alexander D. Rowe Wei Wang Olve Moldestad Monica D. Syrstad Geir Slupphaug Lars Eide Arne Klungland Pål Sætrom Luisa Luna Jing Ye Katja Scheffler Magnar Bjørås
author_facet	Gunn A. Hildrestrand Veslemøy Rolseth Nicolas Kunath Rajikala Suganthan Vidar Jensen Anna M. Bugaj Marion S. Fernandez-Berrocal Sunniva B. Sikko Susanne Vetlesen Anna Kuśnierczyk Ann-Karin Olsen Kristine B. Gützkow Alexander D. Rowe Wei Wang Olve Moldestad Monica D. Syrstad Geir Slupphaug Lars Eide Arne Klungland Pål Sætrom Luisa Luna Jing Ye Katja Scheffler Magnar Bjørås
author_sort	Gunn A. Hildrestrand
title	NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
title_short	NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
title_full	NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
title_fullStr	NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
title_full_unstemmed	NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
title_sort	neil1 and neil2 dna glycosylases modulate anxiety and learning in a cooperative manner in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/36b704fa17dc44b1933173201d933187
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NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice

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