Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system

Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radio...

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Autores principales:	C. Guardiola, A. Márquez, M. C. Jiménez-Ramos, J. García López, A. Baratto-Roldán, X. Muñoz-Berbel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/36c6904a35d24ba08f20d42db067cabf
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spelling	oai:doaj.org-article:36c6904a35d24ba08f20d42db067cabf2021-12-02T15:53:10ZDosimetry with gafchromic films based on a new micro-opto-electro-mechanical system10.1038/s41598-021-89602-92045-2322https://doaj.org/article/36c6904a35d24ba08f20d42db067cabf2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89602-9https://doaj.org/toc/2045-2322Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications.C. GuardiolaA. MárquezM. C. Jiménez-RamosJ. García LópezA. Baratto-RoldánX. Muñoz-BerbelNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q C. Guardiola A. Márquez M. C. Jiménez-Ramos J. García López A. Baratto-Roldán X. Muñoz-Berbel Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
description	Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications.
format	article
author	C. Guardiola A. Márquez M. C. Jiménez-Ramos J. García López A. Baratto-Roldán X. Muñoz-Berbel
author_facet	C. Guardiola A. Márquez M. C. Jiménez-Ramos J. García López A. Baratto-Roldán X. Muñoz-Berbel
author_sort	C. Guardiola
title	Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_short	Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full	Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_fullStr	Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full_unstemmed	Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_sort	dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/36c6904a35d24ba08f20d42db067cabf
work_keys_str_mv	AT cguardiola dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem AT amarquez dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem AT mcjimenezramos dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem AT jgarcialopez dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem AT abarattoroldan dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem AT xmunozberbel dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
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Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system

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