A general 11C-labeling approach enabled by fluoride-mediated desilylation of organosilanes

Convenient and fast methods to introduce 11C into organic molecules are of great help for molecular imaging studies. Here, the authors developed an efficient incorporation of [11C]CO2 and [11C]CH3I into molecules via a fluoride-mediated desilylation process.

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Detalles Bibliográficos
Autores principales: Wenchao Qu, Bao Hu, John W. Babich, Nicole Waterhouse, Marybeth Dooley, Shashikanth Ponnala, Julie Urgiles
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/36c86449efb34b8ea72c8e66f8f2890f
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