Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Mouse models are an essential tool in breast cancer research. Here, the authors present the genomic and transcriptomic profiles of two widely used mouse models, revealing parallels with the human disease specifically with metastasis and treatment response.

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Detalles Bibliográficos
Autores principales: Jonathan P. Rennhack, Briana To, Matthew Swiatnicki, Caleb Dulak, Martin P. Ogrodzinski, Yueqi Zhang, Caralynn Li, Evan Bylett, Christina Ross, Karol Szczepanek, William Hanrahan, Muthu Jayatissa, Sophia Y. Lunt, Kent Hunter, Eran R. Andrechek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/36cd74040a764c95a84c39189bb4072a
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Sumario:Mouse models are an essential tool in breast cancer research. Here, the authors present the genomic and transcriptomic profiles of two widely used mouse models, revealing parallels with the human disease specifically with metastasis and treatment response.