Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Mouse models are an essential tool in breast cancer research. Here, the authors present the genomic and transcriptomic profiles of two widely used mouse models, revealing parallels with the human disease specifically with metastasis and treatment response.

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Autores principales: Jonathan P. Rennhack, Briana To, Matthew Swiatnicki, Caleb Dulak, Martin P. Ogrodzinski, Yueqi Zhang, Caralynn Li, Evan Bylett, Christina Ross, Karol Szczepanek, William Hanrahan, Muthu Jayatissa, Sophia Y. Lunt, Kent Hunter, Eran R. Andrechek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/36cd74040a764c95a84c39189bb4072a
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spelling oai:doaj.org-article:36cd74040a764c95a84c39189bb4072a2021-12-02T15:35:47ZIntegrated analyses of murine breast cancer models reveal critical parallels with human disease10.1038/s41467-019-11236-32041-1723https://doaj.org/article/36cd74040a764c95a84c39189bb4072a2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11236-3https://doaj.org/toc/2041-1723Mouse models are an essential tool in breast cancer research. Here, the authors present the genomic and transcriptomic profiles of two widely used mouse models, revealing parallels with the human disease specifically with metastasis and treatment response.Jonathan P. RennhackBriana ToMatthew SwiatnickiCaleb DulakMartin P. OgrodzinskiYueqi ZhangCaralynn LiEvan BylettChristina RossKarol SzczepanekWilliam HanrahanMuthu JayatissaSophia Y. LuntKent HunterEran R. AndrechekNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jonathan P. Rennhack
Briana To
Matthew Swiatnicki
Caleb Dulak
Martin P. Ogrodzinski
Yueqi Zhang
Caralynn Li
Evan Bylett
Christina Ross
Karol Szczepanek
William Hanrahan
Muthu Jayatissa
Sophia Y. Lunt
Kent Hunter
Eran R. Andrechek
Integrated analyses of murine breast cancer models reveal critical parallels with human disease
description Mouse models are an essential tool in breast cancer research. Here, the authors present the genomic and transcriptomic profiles of two widely used mouse models, revealing parallels with the human disease specifically with metastasis and treatment response.
format article
author Jonathan P. Rennhack
Briana To
Matthew Swiatnicki
Caleb Dulak
Martin P. Ogrodzinski
Yueqi Zhang
Caralynn Li
Evan Bylett
Christina Ross
Karol Szczepanek
William Hanrahan
Muthu Jayatissa
Sophia Y. Lunt
Kent Hunter
Eran R. Andrechek
author_facet Jonathan P. Rennhack
Briana To
Matthew Swiatnicki
Caleb Dulak
Martin P. Ogrodzinski
Yueqi Zhang
Caralynn Li
Evan Bylett
Christina Ross
Karol Szczepanek
William Hanrahan
Muthu Jayatissa
Sophia Y. Lunt
Kent Hunter
Eran R. Andrechek
author_sort Jonathan P. Rennhack
title Integrated analyses of murine breast cancer models reveal critical parallels with human disease
title_short Integrated analyses of murine breast cancer models reveal critical parallels with human disease
title_full Integrated analyses of murine breast cancer models reveal critical parallels with human disease
title_fullStr Integrated analyses of murine breast cancer models reveal critical parallels with human disease
title_full_unstemmed Integrated analyses of murine breast cancer models reveal critical parallels with human disease
title_sort integrated analyses of murine breast cancer models reveal critical parallels with human disease
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/36cd74040a764c95a84c39189bb4072a
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