Palindromic sequence artifacts generated during next generation sequencing library preparation from historic and ancient DNA.

Degradation-specific processes and variation in laboratory protocols can bias the DNA sequence composition from samples of ancient or historic origin. Here, we identify a novel artifact in sequences from historic samples of Atlantic cod (Gadus morhua), which forms interrupted palindromes consisting...

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Autores principales: Bastiaan Star, Alexander J Nederbragt, Marianne H S Hansen, Morten Skage, Gregor D Gilfillan, Ian R Bradbury, Christophe Pampoulie, Nils Chr Stenseth, Kjetill S Jakobsen, Sissel Jentoft
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/36d00581681348debd4ee9296b31aecb
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