Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer

Pancreatic cancer is one of the highly malignant tumors of the digestive system, and early metastasis is an important reason for its short survival time. Circulating tumor cells (CTCs) are a type of tumor cells that are released into the bloodstream from the primary tumor and/or metastatic sites, wh...

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Autores principales: YANG Xiaoying, QIN Cheng, ZHAO Bangbo, LI Tianhao, CAO Hongtao, WANG Weibin
Formato: article
Lenguaje:ZH
Publicado: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2021
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Acceso en línea:https://doaj.org/article/36d39e183c0e4d1bb788d92c1dc85b95
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spelling oai:doaj.org-article:36d39e183c0e4d1bb788d92c1dc85b952021-12-01T01:42:26ZDetection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer1674-908110.12290/xhyxzz.2020-0005https://doaj.org/article/36d39e183c0e4d1bb788d92c1dc85b952021-10-01T00:00:00Zhttps://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2020-0005https://doaj.org/toc/1674-9081Pancreatic cancer is one of the highly malignant tumors of the digestive system, and early metastasis is an important reason for its short survival time. Circulating tumor cells (CTCs) are a type of tumor cells that are released into the bloodstream from the primary tumor and/or metastatic sites, which have properties similar to primary tumor cells and are closely related to distant metastasis of tumors. In vitro quantitative detection of CTCs is of great significance in the early diagnosis, auxiliary staging, treatment efficacy, and prognosis evaluation of pancreatic cancer. Here we generally reviewed current research on the CTCs enrichment methods of pancreatic cancer and its application in screening pancreatic cancer and metastasis, and evaluating the prognosis.YANG XiaoyingQIN ChengZHAO BangboLI TianhaoCAO HongtaoWANG WeibinEditorial Office of Medical Journal of Peking Union Medical College Hospitalarticlepancreatic cancercirculating tumor cellsliquid biopsyMedicineRZHXiehe Yixue Zazhi, Vol 12, Iss 5, Pp 768-773 (2021)
institution DOAJ
collection DOAJ
language ZH
topic pancreatic cancer
circulating tumor cells
liquid biopsy
Medicine
R
spellingShingle pancreatic cancer
circulating tumor cells
liquid biopsy
Medicine
R
YANG Xiaoying
QIN Cheng
ZHAO Bangbo
LI Tianhao
CAO Hongtao
WANG Weibin
Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
description Pancreatic cancer is one of the highly malignant tumors of the digestive system, and early metastasis is an important reason for its short survival time. Circulating tumor cells (CTCs) are a type of tumor cells that are released into the bloodstream from the primary tumor and/or metastatic sites, which have properties similar to primary tumor cells and are closely related to distant metastasis of tumors. In vitro quantitative detection of CTCs is of great significance in the early diagnosis, auxiliary staging, treatment efficacy, and prognosis evaluation of pancreatic cancer. Here we generally reviewed current research on the CTCs enrichment methods of pancreatic cancer and its application in screening pancreatic cancer and metastasis, and evaluating the prognosis.
format article
author YANG Xiaoying
QIN Cheng
ZHAO Bangbo
LI Tianhao
CAO Hongtao
WANG Weibin
author_facet YANG Xiaoying
QIN Cheng
ZHAO Bangbo
LI Tianhao
CAO Hongtao
WANG Weibin
author_sort YANG Xiaoying
title Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
title_short Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
title_full Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
title_fullStr Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
title_full_unstemmed Detection Technology and Prospects of Clinical Application of Circulating Tumor Cells in Pancreatic Cancer
title_sort detection technology and prospects of clinical application of circulating tumor cells in pancreatic cancer
publisher Editorial Office of Medical Journal of Peking Union Medical College Hospital
publishDate 2021
url https://doaj.org/article/36d39e183c0e4d1bb788d92c1dc85b95
work_keys_str_mv AT yangxiaoying detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
AT qincheng detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
AT zhaobangbo detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
AT litianhao detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
AT caohongtao detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
AT wangweibin detectiontechnologyandprospectsofclinicalapplicationofcirculatingtumorcellsinpancreaticcancer
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