Increased risk of Q151M and K65R mutations in patients failing stavudine-containing first-line antiretroviral therapy in Cambodia.
<h4>Background</h4>Multi-nucleos(t)ide resistance (MNR) mutations including Q151M, K65R mutations, and insertion at codon 69 of HIV-1 reverse transcriptase coding region may confer resistance to all molecules of nucleos(t)ide reverse transcriptase inhibitors (NRTI). The presence of these...
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Auteurs principaux: | Janin Nouhin, Yoann Madec, Nicole Ngo-Giang-Huong, Laurent Ferradini, Eric Nerrienet |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/36d6003aad2f41c4a842e45911a9c53c |
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