Bactericidal Disruption of Magnesium Metallostasis in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Is Counteracted by Mutations in the Metal Ion Transporter CorA

Bactericidal Disruption of Magnesium Metallostasis in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Is Counteracted by Mutations in the Metal Ion Transporter CorA

ABSTRACT A defining characteristic of treating tuberculosis is the need for prolonged administration of multiple drugs. This may be due in part to subpopulations of slowly replicating or nonreplicating Mycobacterium tuberculosis bacilli exhibiting phenotypic tolerance to most antibiotics in the stan...

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Autores principales: Landys Lopez Quezada, Sandra Silve, Mark Kelinske, Amir Liba, Constantino Diaz Gonzalez, Martin Kotev, Laurent Goullieux, Stephanie Sans, Christine Roubert, Sophie Lagrange, Eric Bacqué, Cedric Couturier, Alain Pellet, Isabelle Blanc, Marlène Ferron, Fabrice Debu, Kelin Li, Jeffrey Aubé, Julia Roberts, David Little, Yan Ling, Jun Zhang, Ben Gold, Carl Nathan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
CorA
magnesium
mycobacterium
tuberculosis
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/36d78fae9ed74d22a77a85998cdfb018
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