Fast and Flexible mRNA Vaccine Manufacturing as a Solution to Pandemic Situations by Adopting Chemical Engineering Good Practice—Continuous Autonomous Operation in Stainless Steel Equipment Concepts

Fast and Flexible mRNA Vaccine Manufacturing as a Solution to Pandemic Situations by Adopting Chemical Engineering Good Practice—Continuous Autonomous Operation in Stainless Steel Equipment Concepts

SARS-COVID-19 vaccine supply for the total worldwide population has a bottleneck in manufacturing capacity. Assessment of existing messenger ribonucleic acid (mRNA) vaccine processing shows a need for digital twins enabled by process analytical technology approaches in order to improve process trans...

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Autores principales: Axel Schmidt, Heribert Helgers, Florian Lukas Vetter, Alex Juckers, Jochen Strube
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
mRNA
pDNA
SARS-COVID-19
vaccines
digital twin
process analytical technology
Chemical technology
TP1-1185
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/36df35f292794daaa354e627e9a63b18
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