Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity

The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.

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Autores principales:	Agnieszka Latka, Sebastien Lemire, Dennis Grimon, Dorien Dams, Barbara Maciejewska, Timothy Lu, Zuzanna Drulis-Kawa, Yves Briers
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/36e95705b69246a8b345654cdab5e058
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spelling	oai:doaj.org-article:36e95705b69246a8b345654cdab5e0582021-11-03T21:15:03Z Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity 2150-751110.1128/mBio.00455-21https://doaj.org/article/36e95705b69246a8b345654cdab5e0582021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00455-21https://doaj.org/toc/2150-7511 The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.Agnieszka LatkaSebastien LemireDennis GrimonDorien DamsBarbara MaciejewskaTimothy LuZuzanna Drulis-KawaYves BriersAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Agnieszka Latka Sebastien Lemire Dennis Grimon Dorien Dams Barbara Maciejewska Timothy Lu Zuzanna Drulis-Kawa Yves Briers Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
description	The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.
format	article
author	Agnieszka Latka Sebastien Lemire Dennis Grimon Dorien Dams Barbara Maciejewska Timothy Lu Zuzanna Drulis-Kawa Yves Briers
author_facet	Agnieszka Latka Sebastien Lemire Dennis Grimon Dorien Dams Barbara Maciejewska Timothy Lu Zuzanna Drulis-Kawa Yves Briers
author_sort	Agnieszka Latka
title	Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
title_short	Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
title_full	Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
title_fullStr	Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
title_full_unstemmed	Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
title_sort	engineering the modular receptor-binding proteins of <i>klebsiella</i> phages switches their capsule serotype specificity
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/36e95705b69246a8b345654cdab5e058
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Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity

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