Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.
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Nature Portfolio
2016
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oai:doaj.org-article:36f03d68691543e08916d8c32551a6b42021-12-02T14:40:16ZHighly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis10.1038/ncomms119172041-1723https://doaj.org/article/36f03d68691543e08916d8c32551a6b42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11917https://doaj.org/toc/2041-1723Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.Shuke WuYi ZhouTianwen WangHeng-Phon TooDaniel I. C. WangZhi LiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Shuke Wu Yi Zhou Tianwen Wang Heng-Phon Too Daniel I. C. Wang Zhi Li Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
description |
Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules. |
format |
article |
author |
Shuke Wu Yi Zhou Tianwen Wang Heng-Phon Too Daniel I. C. Wang Zhi Li |
author_facet |
Shuke Wu Yi Zhou Tianwen Wang Heng-Phon Too Daniel I. C. Wang Zhi Li |
author_sort |
Shuke Wu |
title |
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
title_short |
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
title_full |
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
title_fullStr |
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
title_full_unstemmed |
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
title_sort |
highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/36f03d68691543e08916d8c32551a6b4 |
work_keys_str_mv |
AT shukewu highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis AT yizhou highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis AT tianwenwang highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis AT hengphontoo highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis AT danielicwang highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis AT zhili highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis |
_version_ |
1718390349671432192 |