Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis

Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.

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Autores principales: Shuke Wu, Yi Zhou, Tianwen Wang, Heng-Phon Too, Daniel I. C. Wang, Zhi Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/36f03d68691543e08916d8c32551a6b4
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spelling oai:doaj.org-article:36f03d68691543e08916d8c32551a6b42021-12-02T14:40:16ZHighly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis10.1038/ncomms119172041-1723https://doaj.org/article/36f03d68691543e08916d8c32551a6b42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11917https://doaj.org/toc/2041-1723Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.Shuke WuYi ZhouTianwen WangHeng-Phon TooDaniel I. C. WangZhi LiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuke Wu
Yi Zhou
Tianwen Wang
Heng-Phon Too
Daniel I. C. Wang
Zhi Li
Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
description Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.
format article
author Shuke Wu
Yi Zhou
Tianwen Wang
Heng-Phon Too
Daniel I. C. Wang
Zhi Li
author_facet Shuke Wu
Yi Zhou
Tianwen Wang
Heng-Phon Too
Daniel I. C. Wang
Zhi Li
author_sort Shuke Wu
title Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
title_short Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
title_full Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
title_fullStr Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
title_full_unstemmed Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
title_sort highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/36f03d68691543e08916d8c32551a6b4
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AT tianwenwang highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis
AT hengphontoo highlyregioandenantioselectivemultipleoxyandaminofunctionalizationsofalkenesbymodularcascadebiocatalysis
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