Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome that is associated with anemia. Here, the authors examine the role of Nemo-like kinase (NLK) in erythroid cells in the pathogenesis of DBA and as a potential target for therapy.
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2020
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oai:doaj.org-article:36f32df2c5f64f50a787e28db8a527f52021-12-02T16:10:47ZDiamond Blackfan anemia is mediated by hyperactive Nemo-like kinase10.1038/s41467-020-17100-z2041-1723https://doaj.org/article/36f32df2c5f64f50a787e28db8a527f52020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17100-zhttps://doaj.org/toc/2041-1723Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome that is associated with anemia. Here, the authors examine the role of Nemo-like kinase (NLK) in erythroid cells in the pathogenesis of DBA and as a potential target for therapy.M. C. WilkesK. SivaJ. ChenG. VarettiM. Y. YounH. ChaeF. EkR. OlssonT. LundbäckD. P. DeverT. NishimuraA. NarlaB. GladerH. NakauchiM. H. PorteusC. E. RepellinH. T. GazdaS. LinM. SerranoJ. FlygareK. M. SakamotoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q M. C. Wilkes K. Siva J. Chen G. Varetti M. Y. Youn H. Chae F. Ek R. Olsson T. Lundbäck D. P. Dever T. Nishimura A. Narla B. Glader H. Nakauchi M. H. Porteus C. E. Repellin H. T. Gazda S. Lin M. Serrano J. Flygare K. M. Sakamoto Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| description |
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome that is associated with anemia. Here, the authors examine the role of Nemo-like kinase (NLK) in erythroid cells in the pathogenesis of DBA and as a potential target for therapy. |
| format |
article |
| author |
M. C. Wilkes K. Siva J. Chen G. Varetti M. Y. Youn H. Chae F. Ek R. Olsson T. Lundbäck D. P. Dever T. Nishimura A. Narla B. Glader H. Nakauchi M. H. Porteus C. E. Repellin H. T. Gazda S. Lin M. Serrano J. Flygare K. M. Sakamoto |
| author_facet |
M. C. Wilkes K. Siva J. Chen G. Varetti M. Y. Youn H. Chae F. Ek R. Olsson T. Lundbäck D. P. Dever T. Nishimura A. Narla B. Glader H. Nakauchi M. H. Porteus C. E. Repellin H. T. Gazda S. Lin M. Serrano J. Flygare K. M. Sakamoto |
| author_sort |
M. C. Wilkes |
| title |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| title_short |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| title_full |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| title_fullStr |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| title_full_unstemmed |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase |
| title_sort |
diamond blackfan anemia is mediated by hyperactive nemo-like kinase |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/36f32df2c5f64f50a787e28db8a527f5 |
| work_keys_str_mv |
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