Association between hospital liver transplantation volume and mortality after liver re-transplantation.

<h4>Background</h4>The relationship between institutional liver transplantation (LT) case volume and clinical outcomes after liver re-transplantation is yet to be determined.<h4>Methods</h4>Patients who underwent liver re-transplantation between 2007 and 2016 were selected fr...

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Autores principales:	Seung-Young Oh, Eun Jin Jang, Ga Hee Kim, Hannah Lee, Nam-Joon Yi, Seokha Yoo, Bo Rim Kim, Ho Geol Ryu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/36f4aa0c04584dbbacae8fa08c68d3fb
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spelling	oai:doaj.org-article:36f4aa0c04584dbbacae8fa08c68d3fb2021-12-02T20:15:12ZAssociation between hospital liver transplantation volume and mortality after liver re-transplantation.1932-620310.1371/journal.pone.0255655https://doaj.org/article/36f4aa0c04584dbbacae8fa08c68d3fb2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255655https://doaj.org/toc/1932-6203<h4>Background</h4>The relationship between institutional liver transplantation (LT) case volume and clinical outcomes after liver re-transplantation is yet to be determined.<h4>Methods</h4>Patients who underwent liver re-transplantation between 2007 and 2016 were selected from the Korean National Healthcare Insurance Service database. Liver transplant centers were categorized to either high-volume centers (≥ 64 LTs/year) or low-volume centers (< 64 LTs/year) according to the annual LT case volume. In-hospital and long-term mortality after liver re-transplantation were compared.<h4>Results</h4>A total of 258 liver re-transplantations were performed during the study period: 175 liver re-transplantations were performed in 3 high-volume centers and 83 were performed in 21 low-volume centers. In-hospital mortality after liver re-transplantation in high and low-volume centers were 25% and 36% (P = 0.069), respectively. Adjusted in-hospital mortality was not different between low and high-volume centers. Adjusted 1-year mortality was significantly higher in low-volume centers (OR 2.14, 95% CI 1.05-4.37, P = 0.037) compared to high-volume centers. Long-term survival for up to 9 years was also superior in high-volume centers (P = 0.005). Other risk factors of in-hospital mortality and 1-year mortality included female sex and higher Elixhauser comorbidity index.<h4>Conclusion</h4>Centers with higher case volume (≥ 64 LTs/year) showed lower in-hospital and overall mortality after liver re-transplantation compared to low-volume centers.Seung-Young OhEun Jin JangGa Hee KimHannah LeeNam-Joon YiSeokha YooBo Rim KimHo Geol RyuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255655 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Seung-Young Oh Eun Jin Jang Ga Hee Kim Hannah Lee Nam-Joon Yi Seokha Yoo Bo Rim Kim Ho Geol Ryu Association between hospital liver transplantation volume and mortality after liver re-transplantation.
description	<h4>Background</h4>The relationship between institutional liver transplantation (LT) case volume and clinical outcomes after liver re-transplantation is yet to be determined.<h4>Methods</h4>Patients who underwent liver re-transplantation between 2007 and 2016 were selected from the Korean National Healthcare Insurance Service database. Liver transplant centers were categorized to either high-volume centers (≥ 64 LTs/year) or low-volume centers (< 64 LTs/year) according to the annual LT case volume. In-hospital and long-term mortality after liver re-transplantation were compared.<h4>Results</h4>A total of 258 liver re-transplantations were performed during the study period: 175 liver re-transplantations were performed in 3 high-volume centers and 83 were performed in 21 low-volume centers. In-hospital mortality after liver re-transplantation in high and low-volume centers were 25% and 36% (P = 0.069), respectively. Adjusted in-hospital mortality was not different between low and high-volume centers. Adjusted 1-year mortality was significantly higher in low-volume centers (OR 2.14, 95% CI 1.05-4.37, P = 0.037) compared to high-volume centers. Long-term survival for up to 9 years was also superior in high-volume centers (P = 0.005). Other risk factors of in-hospital mortality and 1-year mortality included female sex and higher Elixhauser comorbidity index.<h4>Conclusion</h4>Centers with higher case volume (≥ 64 LTs/year) showed lower in-hospital and overall mortality after liver re-transplantation compared to low-volume centers.
format	article
author	Seung-Young Oh Eun Jin Jang Ga Hee Kim Hannah Lee Nam-Joon Yi Seokha Yoo Bo Rim Kim Ho Geol Ryu
author_facet	Seung-Young Oh Eun Jin Jang Ga Hee Kim Hannah Lee Nam-Joon Yi Seokha Yoo Bo Rim Kim Ho Geol Ryu
author_sort	Seung-Young Oh
title	Association between hospital liver transplantation volume and mortality after liver re-transplantation.
title_short	Association between hospital liver transplantation volume and mortality after liver re-transplantation.
title_full	Association between hospital liver transplantation volume and mortality after liver re-transplantation.
title_fullStr	Association between hospital liver transplantation volume and mortality after liver re-transplantation.
title_full_unstemmed	Association between hospital liver transplantation volume and mortality after liver re-transplantation.
title_sort	association between hospital liver transplantation volume and mortality after liver re-transplantation.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/36f4aa0c04584dbbacae8fa08c68d3fb
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Association between hospital liver transplantation volume and mortality after liver re-transplantation.

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