Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials

Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Samira Eghbali, Sayyedeh Fatemeh Askari, Razieh Avan, Amirhossein Sahebkar
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/37017f5b9af247b485f889ed9441542c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:37017f5b9af247b485f889ed9441542c
record_format	dspace
spelling	oai:doaj.org-article:37017f5b9af247b485f889ed9441542c2021-11-29T00:55:54ZTherapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials2090-073210.1155/2021/5297162https://doaj.org/article/37017f5b9af247b485f889ed9441542c2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/5297162https://doaj.org/toc/2090-0732Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.Samira EghbaliSayyedeh Fatemeh AskariRazieh AvanAmirhossein SahebkarHindawi LimitedarticleNutritional diseases. Deficiency diseasesRC620-627ENJournal of Nutrition and Metabolism, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	Nutritional diseases. Deficiency diseases RC620-627 Samira Eghbali Sayyedeh Fatemeh Askari Razieh Avan Amirhossein Sahebkar Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
description	Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.
format	article
author	Samira Eghbali Sayyedeh Fatemeh Askari Razieh Avan Amirhossein Sahebkar
author_facet	Samira Eghbali Sayyedeh Fatemeh Askari Razieh Avan Amirhossein Sahebkar
author_sort	Samira Eghbali
title	Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
title_short	Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
title_full	Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
title_fullStr	Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
title_full_unstemmed	Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
title_sort	therapeutic effects of punica granatum (pomegranate): an updated review of clinical trials
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/37017f5b9af247b485f889ed9441542c
work_keys_str_mv	AT samiraeghbali therapeuticeffectsofpunicagranatumpomegranateanupdatedreviewofclinicaltrials AT sayyedehfatemehaskari therapeuticeffectsofpunicagranatumpomegranateanupdatedreviewofclinicaltrials AT raziehavan therapeuticeffectsofpunicagranatumpomegranateanupdatedreviewofclinicaltrials AT amirhosseinsahebkar therapeuticeffectsofpunicagranatumpomegranateanupdatedreviewofclinicaltrials
_version_	1718407762269962240

Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials

Ejemplares similares