Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear. Here the authors show that, in activated T cells, the Golgin GMAP210 specifically conveys LAT+ vesicles to immune synapse allowi...

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Autores principales:	Andres Ernesto Zucchetti, Laurence Bataille, Jean-Marie Carpier, Stéphanie Dogniaux, Mabel San Roman-Jouve, Mathieu Maurin, Michael W. Stuck, Rosa M. Rios, Cosima T. Baldari, Gregory J. Pazour, Claire Hivroz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/370bbd7397c540fe9d6af37f4e80670b
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spelling	oai:doaj.org-article:370bbd7397c540fe9d6af37f4e80670b2021-12-02T14:38:42ZTethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse10.1038/s41467-019-10891-w2041-1723https://doaj.org/article/370bbd7397c540fe9d6af37f4e80670b2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10891-whttps://doaj.org/toc/2041-1723The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear. Here the authors show that, in activated T cells, the Golgin GMAP210 specifically conveys LAT+ vesicles to immune synapse allowing proper T cell activation.Andres Ernesto ZucchettiLaurence BatailleJean-Marie CarpierStéphanie DogniauxMabel San Roman-JouveMathieu MaurinMichael W. StuckRosa M. RiosCosima T. BaldariGregory J. PazourClaire HivrozNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andres Ernesto Zucchetti Laurence Bataille Jean-Marie Carpier Stéphanie Dogniaux Mabel San Roman-Jouve Mathieu Maurin Michael W. Stuck Rosa M. Rios Cosima T. Baldari Gregory J. Pazour Claire Hivroz Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
description	The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear. Here the authors show that, in activated T cells, the Golgin GMAP210 specifically conveys LAT+ vesicles to immune synapse allowing proper T cell activation.
format	article
author	Andres Ernesto Zucchetti Laurence Bataille Jean-Marie Carpier Stéphanie Dogniaux Mabel San Roman-Jouve Mathieu Maurin Michael W. Stuck Rosa M. Rios Cosima T. Baldari Gregory J. Pazour Claire Hivroz
author_facet	Andres Ernesto Zucchetti Laurence Bataille Jean-Marie Carpier Stéphanie Dogniaux Mabel San Roman-Jouve Mathieu Maurin Michael W. Stuck Rosa M. Rios Cosima T. Baldari Gregory J. Pazour Claire Hivroz
author_sort	Andres Ernesto Zucchetti
title	Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
title_short	Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
title_full	Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
title_fullStr	Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
title_full_unstemmed	Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
title_sort	tethering of vesicles to the golgi by gmap210 controls lat delivery to the immune synapse
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/370bbd7397c540fe9d6af37f4e80670b
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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

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