Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

Methionine availability is known to affect the global levels of histone methylation. Here the authors investigate the metabolically driven dynamics of H3K4me3 and find that methionine availability influences peak width, which is linked to changes in expression of genes associated with cell fate and...

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Autores principales: Ziwei Dai, Samantha J. Mentch, Xia Gao, Sailendra N. Nichenametla, Jason W. Locasale
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/3713a74cedbd488f8170cdb32441a952
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